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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKX6-3
All Species:
20.91
Human Site:
S135
Identified Species:
41.82
UniProt:
A6NJ46
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NJ46
NP_689781.1
265
28948
S135
T
P
D
P
L
S
D
S
I
H
K
K
K
H
T
Chimpanzee
Pan troglodytes
XP_001138968
265
28831
S135
T
P
D
P
L
S
D
S
I
H
K
K
K
H
T
Rhesus Macaque
Macaca mulatta
XP_001094557
265
28927
S135
T
P
D
P
L
S
D
S
I
H
K
K
K
H
T
Dog
Lupus familis
XP_849158
262
28455
S135
T
P
D
P
L
S
D
S
I
H
K
K
K
H
T
Cat
Felis silvestris
Mouse
Mus musculus
Q3UHX8
262
28761
D135
N
T
P
D
P
L
S
D
T
I
H
K
K
K
H
Rat
Rattus norvegicus
O35762
365
37671
K233
Q
G
S
I
L
L
D
K
D
G
K
R
K
H
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510049
265
28997
S135
T
P
D
P
L
S
D
S
I
H
K
K
K
H
T
Chicken
Gallus gallus
O93367
297
32351
T168
G
H
P
Y
Q
N
R
T
P
P
K
R
K
K
P
Frog
Xenopus laevis
A5YC49
254
27880
S130
S
A
S
N
T
E
G
S
S
R
K
K
H
T
R
Zebra Danio
Brachydanio rerio
Q504H8
297
33069
K166
S
D
D
G
A
D
K
K
P
C
R
K
K
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P56407
147
17231
P23
L
L
T
S
D
V
K
P
Q
R
R
T
S
H
L
Sea Urchin
Strong. purpuratus
Q26656
405
44721
P249
D
D
D
D
D
Q
S
P
Q
K
K
K
K
K
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.4
92.4
N.A.
93.9
40.5
N.A.
91.6
26.2
58.4
23.9
N.A.
N.A.
N.A.
26
23.9
Protein Similarity:
100
99.6
98.8
93.9
N.A.
95.4
49
N.A.
93.5
38.7
70.9
37.7
N.A.
N.A.
N.A.
37.7
37.2
P-Site Identity:
100
100
100
100
N.A.
13.3
40
N.A.
100
13.3
20
26.6
N.A.
N.A.
N.A.
6.6
33.3
P-Site Similarity:
100
100
100
100
N.A.
13.3
46.6
N.A.
100
33.3
26.6
40
N.A.
N.A.
N.A.
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
9
17
59
17
17
9
50
9
9
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
9
0
9
0
0
9
0
0
9
0
0
0
0
0
% G
% His:
0
9
0
0
0
0
0
0
0
42
9
0
9
59
9
% H
% Ile:
0
0
0
9
0
0
0
0
42
9
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
17
17
0
9
75
75
84
34
0
% K
% Leu:
9
9
0
0
50
17
0
0
0
0
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
9
0
9
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
42
17
42
9
0
0
17
17
9
0
0
0
0
9
% P
% Gln:
9
0
0
0
9
9
0
0
17
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
9
0
0
17
17
17
0
0
9
% R
% Ser:
17
0
17
9
0
42
17
50
9
0
0
0
9
0
0
% S
% Thr:
42
9
9
0
9
0
0
9
9
0
0
9
0
9
67
% T
% Val:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _