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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKX6-3
All Species:
22.12
Human Site:
S85
Identified Species:
44.24
UniProt:
A6NJ46
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NJ46
NP_689781.1
265
28948
S85
A
G
F
G
G
L
S
S
Q
G
V
Y
Y
S
P
Chimpanzee
Pan troglodytes
XP_001138968
265
28831
S85
A
G
F
G
G
L
S
S
Q
G
V
Y
Y
S
P
Rhesus Macaque
Macaca mulatta
XP_001094557
265
28927
S85
A
G
F
G
G
L
S
S
Q
G
V
Y
Y
S
P
Dog
Lupus familis
XP_849158
262
28455
S85
A
G
F
G
G
L
G
S
Q
G
V
Y
Y
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3UHX8
262
28761
S85
A
G
F
G
G
L
S
S
Q
G
V
Y
Y
G
P
Rat
Rattus norvegicus
O35762
365
37671
A183
L
Y
F
S
P
S
A
A
A
V
A
A
V
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510049
265
28997
S85
A
G
F
S
G
L
S
S
Q
G
V
Y
Y
G
P
Chicken
Gallus gallus
O93367
297
32351
S118
A
V
P
P
P
V
P
S
A
I
P
A
V
P
G
Frog
Xenopus laevis
A5YC49
254
27880
V80
Q
G
Y
G
S
S
S
V
P
G
T
C
Y
G
E
Zebra Danio
Brachydanio rerio
Q504H8
297
33069
L116
T
D
R
D
S
P
E
L
V
L
K
S
D
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P56407
147
17231
Sea Urchin
Strong. purpuratus
Q26656
405
44721
K199
S
S
R
L
A
M
A
K
D
I
S
P
R
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.4
92.4
N.A.
93.9
40.5
N.A.
91.6
26.2
58.4
23.9
N.A.
N.A.
N.A.
26
23.9
Protein Similarity:
100
99.6
98.8
93.9
N.A.
95.4
49
N.A.
93.5
38.7
70.9
37.7
N.A.
N.A.
N.A.
37.7
37.2
P-Site Identity:
100
100
100
86.6
N.A.
93.3
6.6
N.A.
86.6
13.3
33.3
0
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
20
N.A.
86.6
20
40
0
N.A.
N.A.
N.A.
0
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
59
0
0
0
9
0
17
9
17
0
9
17
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
9
0
9
0
0
0
0
9
0
0
0
9
0
9
% D
% Glu:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% E
% Phe:
0
0
59
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
59
0
50
50
0
9
0
0
59
0
0
0
42
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% K
% Leu:
9
0
0
9
0
50
0
9
0
9
0
0
0
0
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
9
9
17
9
9
0
9
0
9
9
0
25
50
% P
% Gln:
9
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% Q
% Arg:
0
0
17
0
0
0
0
0
0
0
0
0
9
0
9
% R
% Ser:
9
9
0
17
17
17
50
59
0
0
9
9
0
25
0
% S
% Thr:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% T
% Val:
0
9
0
0
0
9
0
9
9
9
50
0
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
9
0
0
0
0
0
0
0
0
50
59
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _