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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METT5D1
All Species:
26.97
Human Site:
Y246
Identified Species:
65.93
UniProt:
A6NJ78
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NJ78
NP_001107000.1
407
46121
Y246
I
V
Q
A
R
S
I
Y
P
I
T
R
T
Q
Q
Chimpanzee
Pan troglodytes
XP_508346
407
46088
Y246
I
V
Q
A
R
S
I
Y
P
I
T
R
T
Q
Q
Rhesus Macaque
Macaca mulatta
XP_001088477
437
49563
Y279
I
V
Q
A
R
S
I
Y
P
I
T
R
T
Q
Q
Dog
Lupus familis
XP_534100
694
75048
Y533
I
V
Q
A
R
S
L
Y
P
I
S
R
T
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCL4
406
45263
Y246
I
I
Q
A
R
S
T
Y
P
I
S
R
T
Q
Q
Rat
Rattus norvegicus
NP_001020152
286
31731
R130
V
A
F
T
L
A
E
R
L
S
E
M
Y
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510902
436
48642
Y275
I
V
Q
A
R
T
I
Y
P
I
T
R
T
Q
Q
Chicken
Gallus gallus
XP_419643
475
52323
Y314
I
V
Q
A
R
S
I
Y
P
I
T
R
T
Q
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689063
402
44597
P242
A
Q
A
R
S
V
Y
P
I
G
R
T
L
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGY5
356
39684
N200
R
G
L
V
D
A
R
N
A
L
F
K
I
E
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
84.9
50
N.A.
78.3
52.8
N.A.
65.8
57.6
N.A.
51.5
N.A.
40.2
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
86.5
54.4
N.A.
87.4
59.2
N.A.
76.1
69.8
N.A.
66.3
N.A.
55.7
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
80
0
N.A.
93.3
100
N.A.
6.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
13.3
N.A.
100
100
N.A.
6.6
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
70
0
20
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
10
0
0
10
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
70
10
0
0
0
0
50
0
10
70
0
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
0
0
10
0
10
0
10
0
10
10
0
0
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
70
0
0
0
0
10
0
% P
% Gln:
0
10
70
0
0
0
0
0
0
0
0
0
0
80
70
% Q
% Arg:
10
0
0
10
70
0
10
10
0
0
10
70
0
0
0
% R
% Ser:
0
0
0
0
10
60
0
0
0
10
20
0
0
0
0
% S
% Thr:
0
0
0
10
0
10
10
0
0
0
50
10
70
0
20
% T
% Val:
10
60
0
10
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
70
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _