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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 4.85
Human Site: T254 Identified Species: 17.78
UniProt: A6NJI9 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NJI9 XP_002344333 287 33656 T254 S M K R S V M T L T S M N W D
Chimpanzee Pan troglodytes XP_001150272 344 40053 T311 S M K R S V M T L T S M N W D
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P57784 255 28339 L223 E V E R L K G L L Q S G Q I P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509005 255 28376 L223 E V E R L K G L L Q S G Q I P
Chicken Gallus gallus XP_418694 157 17925 N125 I I S L R T L N L F Y N P L A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9BLB6 253 28846 N221 A K S L S E V N Y L Q S I L A
Sea Urchin Strong. purpuratus XP_789351 260 29983 S228 Q R S I M E Y S H F D W T K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.2 N.A. N.A. N.A. 26.1 N.A. N.A. 24 28.2 N.A. N.A. N.A. N.A. N.A. 20.5 32
Protein Similarity: 100 82.8 N.A. N.A. N.A. 42.1 N.A. N.A. 41.8 41.4 N.A. N.A. N.A. N.A. N.A. 41.8 52.9
P-Site Identity: 100 100 N.A. N.A. N.A. 20 N.A. N.A. 20 6.6 N.A. N.A. N.A. N.A. N.A. 6.6 0
P-Site Similarity: 100 100 N.A. N.A. N.A. 33.3 N.A. N.A. 33.3 20 N.A. N.A. N.A. N.A. N.A. 20 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 0 0 0 0 0 0 0 0 0 0 0 0 29 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 15 0 0 0 29 % D
% Glu: 29 0 29 0 0 29 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 29 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 29 0 0 0 0 29 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % H
% Ile: 15 15 0 15 0 0 0 0 0 0 0 0 15 29 0 % I
% Lys: 0 15 29 0 0 29 0 0 0 0 0 0 0 15 15 % K
% Leu: 0 0 0 29 29 0 15 29 72 15 0 0 0 29 0 % L
% Met: 0 29 0 0 15 0 29 0 0 0 0 29 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 29 0 0 0 15 29 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 29 % P
% Gln: 15 0 0 0 0 0 0 0 0 29 15 0 29 0 0 % Q
% Arg: 0 15 0 58 15 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 29 0 43 0 43 0 0 15 0 0 58 15 0 0 0 % S
% Thr: 0 0 0 0 0 15 0 29 0 29 0 0 15 0 0 % T
% Val: 0 29 0 0 0 29 15 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 15 0 29 0 % W
% Tyr: 0 0 0 0 0 0 15 0 15 0 15 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _