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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 1.82
Human Site: T278 Identified Species: 6.67
UniProt: A6NJI9 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NJI9 XP_002344333 287 33656 T278 L E E E G T E T A Q M L T V T
Chimpanzee Pan troglodytes XP_001150272 344 40053 P335 L E E E G T E P A Q M L T V T
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P57784 255 28339 E247 D E G E E E I E D D T V T N G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509005 255 28376 E247 D D G E E E M E E D P V T N G
Chicken Gallus gallus XP_418694 157 17925 Q149 I H S L P S V Q L L D R K R K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9BLB6 253 28846 G245 N R Q M D Q N G A D G E A M E
Sea Urchin Strong. purpuratus XP_789351 260 29983 T252 K N V E G S K T E I I T V R F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.2 N.A. N.A. N.A. 26.1 N.A. N.A. 24 28.2 N.A. N.A. N.A. N.A. N.A. 20.5 32
Protein Similarity: 100 82.8 N.A. N.A. N.A. 42.1 N.A. N.A. 41.8 41.4 N.A. N.A. N.A. N.A. N.A. 41.8 52.9
P-Site Identity: 100 93.3 N.A. N.A. N.A. 20 N.A. N.A. 13.3 0 N.A. N.A. N.A. N.A. N.A. 6.6 20
P-Site Similarity: 100 93.3 N.A. N.A. N.A. 26.6 N.A. N.A. 26.6 13.3 N.A. N.A. N.A. N.A. N.A. 20 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 43 0 0 0 15 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 29 15 0 0 15 0 0 0 15 43 15 0 0 0 0 % D
% Glu: 0 43 29 72 29 29 29 29 29 0 0 15 0 0 15 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 % F
% Gly: 0 0 29 0 43 0 0 15 0 0 15 0 0 0 29 % G
% His: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 15 0 0 0 0 0 15 0 0 15 15 0 0 0 0 % I
% Lys: 15 0 0 0 0 0 15 0 0 0 0 0 15 0 15 % K
% Leu: 29 0 0 15 0 0 0 0 15 15 0 29 0 0 0 % L
% Met: 0 0 0 15 0 0 15 0 0 0 29 0 0 15 0 % M
% Asn: 15 15 0 0 0 0 15 0 0 0 0 0 0 29 0 % N
% Pro: 0 0 0 0 15 0 0 15 0 0 15 0 0 0 0 % P
% Gln: 0 0 15 0 0 15 0 15 0 29 0 0 0 0 0 % Q
% Arg: 0 15 0 0 0 0 0 0 0 0 0 15 0 29 0 % R
% Ser: 0 0 15 0 0 29 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 29 0 29 0 0 15 15 58 0 29 % T
% Val: 0 0 15 0 0 0 15 0 0 0 0 29 15 29 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _