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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRG1
All Species:
4.55
Human Site:
S431
Identified Species:
12.5
UniProt:
A6NK06
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NK06
XP_001133269
481
52628
S431
A
N
A
S
K
M
L
S
W
D
T
V
E
S
L
Chimpanzee
Pan troglodytes
XP_001137876
568
62456
S503
A
N
A
S
K
M
L
S
W
D
T
V
E
S
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542615
519
56447
F470
Q
E
D
L
R
E
K
F
R
A
N
A
S
S
M
Cat
Felis silvestris
Mouse
Mus musculus
P54987
488
53740
C432
A
N
A
S
K
M
L
C
R
D
T
V
E
S
L
Rat
Rattus norvegicus
NP_001100752
488
53597
G432
A
N
A
S
K
I
L
G
E
D
T
V
E
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518120
461
49817
V412
D
L
E
D
K
F
R
V
N
A
S
T
A
L
C
Chicken
Gallus gallus
NP_001025992
478
52360
E429
K
F
Q
S
N
A
S
E
V
L
P
A
E
A
I
Frog
Xenopus laevis
NP_001081912
498
54691
W448
T
D
T
F
Y
G
H
W
R
N
P
L
S
R
E
Zebra Danio
Brachydanio rerio
NP_001071075
498
54081
W448
C
D
T
F
Y
G
H
W
R
N
P
L
S
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.2
N.A.
76.4
N.A.
80.9
81.3
N.A.
61.5
64.6
51.4
52.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
83.4
N.A.
83.8
N.A.
88.9
89.9
N.A.
75.6
79
68.6
68.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
6.6
N.A.
86.6
80
N.A.
6.6
13.3
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
20
N.A.
86.6
86.6
N.A.
13.3
26.6
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
45
0
45
0
0
12
0
0
0
23
0
23
12
12
0
% A
% Cys:
12
0
0
0
0
0
0
12
0
0
0
0
0
0
12
% C
% Asp:
12
23
12
12
0
0
0
0
0
45
0
0
0
0
0
% D
% Glu:
0
12
12
0
0
12
0
12
12
0
0
0
56
0
23
% E
% Phe:
0
12
0
23
0
12
0
12
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
23
0
12
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
23
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
12
% I
% Lys:
12
0
0
0
56
0
12
0
0
0
0
0
0
0
0
% K
% Leu:
0
12
0
12
0
0
45
0
0
12
0
23
0
12
45
% L
% Met:
0
0
0
0
0
34
0
0
0
0
0
0
0
0
12
% M
% Asn:
0
45
0
0
12
0
0
0
12
23
12
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
34
0
0
0
0
% P
% Gln:
12
0
12
0
0
0
0
0
0
0
0
0
0
12
0
% Q
% Arg:
0
0
0
0
12
0
12
0
45
0
0
0
0
12
0
% R
% Ser:
0
0
0
56
0
0
12
23
0
0
12
0
34
56
0
% S
% Thr:
12
0
23
0
0
0
0
0
0
0
45
12
0
0
0
% T
% Val:
0
0
0
0
0
0
0
12
12
0
0
45
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
23
23
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
23
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _