KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRG1
All Species:
6.97
Human Site:
S470
Identified Species:
19.17
UniProt:
A6NK06
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NK06
XP_001133269
481
52628
S470
P
P
E
V
A
S
N
S
P
A
C
N
N
S
I
Chimpanzee
Pan troglodytes
XP_001137876
568
62456
S542
P
P
E
V
A
S
N
S
P
A
C
N
N
L
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542615
519
56447
P509
L
T
T
L
L
K
G
P
P
P
P
E
M
A
S
Cat
Felis silvestris
Mouse
Mus musculus
P54987
488
53740
L471
V
Q
D
E
A
S
K
L
S
S
M
S
S
F
D
Rat
Rattus norvegicus
NP_001100752
488
53597
L471
V
Q
E
E
A
S
K
L
S
S
I
F
S
F
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518120
461
49817
S451
T
C
L
K
G
T
S
S
P
K
E
G
S
K
M
Chicken
Gallus gallus
NP_001025992
478
52360
P468
G
Q
S
A
R
L
L
P
E
K
L
H
V
E
H
Frog
Xenopus laevis
NP_001081912
498
54691
V487
M
V
E
N
M
E
S
V
S
D
V
S
Q
L
P
Zebra Danio
Brachydanio rerio
NP_001071075
498
54081
S487
A
V
E
S
L
D
R
S
D
D
C
K
Q
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.2
N.A.
76.4
N.A.
80.9
81.3
N.A.
61.5
64.6
51.4
52.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
83.4
N.A.
83.8
N.A.
88.9
89.9
N.A.
75.6
79
68.6
68.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
86.6
N.A.
6.6
N.A.
13.3
20
N.A.
13.3
0
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
N.A.
20
N.A.
40
33.3
N.A.
40
6.6
20
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
12
45
0
0
0
0
23
0
0
0
12
0
% A
% Cys:
0
12
0
0
0
0
0
0
0
0
34
0
0
0
0
% C
% Asp:
0
0
12
0
0
12
0
0
12
23
0
0
0
0
12
% D
% Glu:
0
0
56
23
0
12
0
0
12
0
12
12
0
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
12
0
23
0
% F
% Gly:
12
0
0
0
12
0
12
0
0
0
0
12
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
23
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
12
% I
% Lys:
0
0
0
12
0
12
23
0
0
23
0
12
0
12
0
% K
% Leu:
12
0
12
12
23
12
12
23
0
0
12
0
0
34
12
% L
% Met:
12
0
0
0
12
0
0
0
0
0
12
0
12
0
12
% M
% Asn:
0
0
0
12
0
0
23
0
0
0
0
23
23
0
0
% N
% Pro:
23
23
0
0
0
0
0
23
45
12
12
0
0
0
12
% P
% Gln:
0
34
0
0
0
0
0
0
0
0
0
0
23
0
0
% Q
% Arg:
0
0
0
0
12
0
12
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
12
12
0
45
23
45
34
23
0
23
34
12
23
% S
% Thr:
12
12
12
0
0
12
0
0
0
0
0
0
0
0
0
% T
% Val:
23
23
0
23
0
0
0
12
0
0
12
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _