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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 18.48
Human Site: S116 Identified Species: 40.67
UniProt: A6NK25 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NK25 NP_958802 285 31668 S116 H R S Y L L P S G G S V T L S
Chimpanzee Pan troglodytes XP_001174997 436 46878 S249 H R S Y L L T S G G S V T L S
Rhesus Macaque Macaca mulatta XP_001100213 330 36755 S116 H R S Y L L P S G G S V T L S
Dog Lupus familis XP_852896 319 34952 T139 P A A F A H R T V L E L G S G
Cat Felis silvestris
Mouse Mus musculus Q3UZW7 335 36922 S116 H R S Y L L P S G N S V T L S
Rat Rattus norvegicus NP_001100445 335 36972 S116 H R S Y L L P S G D S V T L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001025798 338 37684 I127 T L S E S V A I I S Q G T T G
Frog Xenopus laevis NP_001090098 316 35802 I122 T L C E N V A I I S E G T T G
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573368 319 35261 H144 L G D Y L L Q H R D L V R G K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P30643 371 42049 G144 E R V Y L T D G G D K V L A K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P47163 339 38978 I126 I E E T P N L I S A A S T T G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 55 77.8 59.8 N.A. 61.4 60.9 N.A. N.A. 46.4 45.2 N.A. N.A. 22.2 N.A. 20.7 N.A.
Protein Similarity: 100 58.7 81.2 68.6 N.A. 68.9 68.3 N.A. N.A. 58.2 61 N.A. N.A. 40.4 N.A. 39 N.A.
P-Site Identity: 100 93.3 100 0 N.A. 93.3 93.3 N.A. N.A. 13.3 6.6 N.A. N.A. 26.6 N.A. 33.3 N.A.
P-Site Similarity: 100 93.3 100 26.6 N.A. 93.3 93.3 N.A. N.A. 20 13.3 N.A. N.A. 26.6 N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 38.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 0 10 0 19 0 0 10 10 0 0 10 0 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 10 0 0 28 0 0 0 0 0 % D
% Glu: 10 10 10 19 0 0 0 0 0 0 19 0 0 0 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 0 0 0 10 55 28 0 19 10 10 37 % G
% His: 46 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 28 19 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 19 % K
% Leu: 10 19 0 0 64 55 10 0 0 10 10 10 10 46 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 10 0 0 0 10 0 0 0 0 0 % N
% Pro: 10 0 0 0 10 0 37 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 10 0 0 0 0 % Q
% Arg: 0 55 0 0 0 0 10 0 10 0 0 0 10 0 0 % R
% Ser: 0 0 55 0 10 0 0 46 10 19 46 10 0 10 46 % S
% Thr: 19 0 0 10 0 10 10 10 0 0 0 0 73 28 0 % T
% Val: 0 0 10 0 0 19 0 0 10 0 0 64 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 64 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _