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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 18.79
Human Site: S42 Identified Species: 41.33
UniProt: A6NK25 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NK25 NP_958802 285 31668 S42 E A K L R D S S D S E L L Q D
Chimpanzee Pan troglodytes XP_001174997 436 46878 S175 E A K L R D S S D S E L L R D
Rhesus Macaque Macaca mulatta XP_001100213 330 36755 S42 E A K L R D S S D S E L L R D
Dog Lupus familis XP_852896 319 34952 T65 R K H E A V H T E P L D E L Y
Cat Felis silvestris
Mouse Mus musculus Q3UZW7 335 36922 S42 E E K L K D P S G S E L L L A
Rat Rattus norvegicus NP_001100445 335 36972 S42 E E K L R E P S G S E L L L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001025798 338 37684 T53 L A D I L H Q T V L H P L C V
Frog Xenopus laevis NP_001090098 316 35802 T48 I S Q I L E K T V L H P L C Q
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573368 319 35261 G70 K H L L L L L G D Q E D L H D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P30643 371 42049 K70 D I V E Q C I K D S E Y A E N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P47163 339 38978 C52 Q K T N A Y Y C K T I V K M L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 55 77.8 59.8 N.A. 61.4 60.9 N.A. N.A. 46.4 45.2 N.A. N.A. 22.2 N.A. 20.7 N.A.
Protein Similarity: 100 58.7 81.2 68.6 N.A. 68.9 68.3 N.A. N.A. 58.2 61 N.A. N.A. 40.4 N.A. 39 N.A.
P-Site Identity: 100 93.3 93.3 0 N.A. 60 60 N.A. N.A. 13.3 6.6 N.A. N.A. 33.3 N.A. 20 N.A.
P-Site Similarity: 100 100 100 13.3 N.A. 66.6 66.6 N.A. N.A. 26.6 40 N.A. N.A. 40 N.A. 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 38.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 37 0 0 19 0 0 0 0 0 0 0 10 0 19 % A
% Cys: 0 0 0 0 0 10 0 10 0 0 0 0 0 19 0 % C
% Asp: 10 0 10 0 0 37 0 0 46 0 0 19 0 0 37 % D
% Glu: 46 19 0 19 0 19 0 0 10 0 64 0 10 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 10 19 0 0 0 0 0 0 % G
% His: 0 10 10 0 0 10 10 0 0 0 19 0 0 10 0 % H
% Ile: 10 10 0 19 0 0 10 0 0 0 10 0 0 0 0 % I
% Lys: 10 19 46 0 10 0 10 10 10 0 0 0 10 0 0 % K
% Leu: 10 0 10 55 28 10 10 0 0 19 10 46 73 28 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 0 0 19 0 0 10 0 19 0 0 0 % P
% Gln: 10 0 10 0 10 0 10 0 0 10 0 0 0 10 10 % Q
% Arg: 10 0 0 0 37 0 0 0 0 0 0 0 0 19 0 % R
% Ser: 0 10 0 0 0 0 28 46 0 55 0 0 0 0 0 % S
% Thr: 0 0 10 0 0 0 0 28 0 10 0 0 0 0 0 % T
% Val: 0 0 10 0 0 10 0 0 19 0 0 10 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 10 0 0 0 0 10 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _