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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 39.39
Human Site: S194 Identified Species: 86.67
UniProt: A6NK58 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NK58 NP_001138341.1 231 25195 S194 L V G T G V T S L S K E L Q R
Chimpanzee Pan troglodytes XP_508640 287 31281 S250 L V G T G V T S L S K E L Q R
Rhesus Macaque Macaca mulatta XP_001111080 231 25142 S194 L V G T G V T S L S K E L Q R
Dog Lupus familis XP_542314 231 25003 S194 L V G T G V T S L S E E L R R
Cat Felis silvestris
Mouse Mus musculus Q9D009 231 24937 S194 L V G T G V T S L S E A L Q R
Rat Rattus norvegicus NP_001102387 231 25179 S194 L V G T G V T S L S E A L Q R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q29R99 224 24646 S187 I V G K G V T S L S Q E L E R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VN27 234 26015 S190 I E G K G V T S L S K E L D R
Honey Bee Apis mellifera XP_001121995 236 26912 S186 I E G K G V T S I S Q E L N R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793736 240 27062 S194 I E G K G V T S L T K E V K D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SXP7 235 26403 S187 I A D K E V T S L R R E T D T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.4 96.5 88.3 N.A. 84.4 83.1 N.A. N.A. N.A. N.A. 48 N.A. 45.2 42.7 N.A. 44.5
Protein Similarity: 100 79.7 98.2 93 N.A. 89.6 89.6 N.A. N.A. N.A. N.A. 64.5 N.A. 59.4 65.2 N.A. 58.3
P-Site Identity: 100 100 100 86.6 N.A. 86.6 86.6 N.A. N.A. N.A. N.A. 73.3 N.A. 73.3 60 N.A. 53.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. N.A. N.A. 93.3 N.A. 80 80 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. 38.7 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 54 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 0 0 0 0 0 19 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 0 0 0 19 10 % D
% Glu: 0 28 0 0 10 0 0 0 0 0 28 82 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 91 0 91 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 46 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 0 0 0 46 0 0 0 0 0 0 46 0 0 10 0 % K
% Leu: 55 0 0 0 0 0 0 0 91 0 0 0 82 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 19 0 0 46 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 10 10 0 0 10 82 % R
% Ser: 0 0 0 0 0 0 0 100 0 82 0 0 0 0 0 % S
% Thr: 0 0 0 55 0 0 100 0 0 10 0 0 10 0 10 % T
% Val: 0 64 0 0 0 100 0 0 0 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _