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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 34.85
Human Site: T143 Identified Species: 76.67
UniProt: A6NK58 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NK58 NP_001138341.1 231 25195 T143 R A R P P P Y T G V W L D D R
Chimpanzee Pan troglodytes XP_508640 287 31281 T199 R A R P P P Y T G V W L D D R
Rhesus Macaque Macaca mulatta XP_001111080 231 25142 T143 R A R S P P Y T G V W L D D R
Dog Lupus familis XP_542314 231 25003 T143 R A R P P P Y T G V W L G E R
Cat Felis silvestris
Mouse Mus musculus Q9D009 231 24937 T143 R A R P P P Y T G V W L G E R
Rat Rattus norvegicus NP_001102387 231 25179 T143 R A R P P P Y T G V W L G E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q29R99 224 24646 T136 K A S T S P D T G V W V G D N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VN27 234 26015 T139 S A K A T K D T G I W V G D N
Honey Bee Apis mellifera XP_001121995 236 26912 T135 K G E K S S D T G I W I N D K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793736 240 27062 T143 E G Q C S P H T G V W V G D S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SXP7 235 26403 T136 R A G N K C E T G V W V G D R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.4 96.5 88.3 N.A. 84.4 83.1 N.A. N.A. N.A. N.A. 48 N.A. 45.2 42.7 N.A. 44.5
Protein Similarity: 100 79.7 98.2 93 N.A. 89.6 89.6 N.A. N.A. N.A. N.A. 64.5 N.A. 59.4 65.2 N.A. 58.3
P-Site Identity: 100 100 93.3 86.6 N.A. 86.6 86.6 N.A. N.A. N.A. N.A. 46.6 N.A. 33.3 26.6 N.A. 40
P-Site Similarity: 100 100 93.3 93.3 N.A. 93.3 93.3 N.A. N.A. N.A. N.A. 60 N.A. 53.3 60 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. 38.7 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 54 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 82 0 10 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 28 0 0 0 0 0 28 73 0 % D
% Glu: 10 0 10 0 0 0 10 0 0 0 0 0 0 28 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 19 10 0 0 0 0 0 100 0 0 0 64 0 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 19 0 10 0 0 0 % I
% Lys: 19 0 10 10 10 10 0 0 0 0 0 0 0 0 10 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 55 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 0 0 10 0 19 % N
% Pro: 0 0 0 46 55 73 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 64 0 55 0 0 0 0 0 0 0 0 0 0 0 64 % R
% Ser: 10 0 10 10 28 10 0 0 0 0 0 0 0 0 10 % S
% Thr: 0 0 0 10 10 0 0 100 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 82 0 37 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 55 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _