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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 24.24
Human Site: Y57 Identified Species: 53.33
UniProt: A6NK58 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NK58 NP_001138341.1 231 25195 Y57 C E P A G P V Y T A G L R G G
Chimpanzee Pan troglodytes XP_508640 287 31281 Y113 C E P A G P V Y T A G L R G G
Rhesus Macaque Macaca mulatta XP_001111080 231 25142 Y57 C E P A G P V Y T A G L R G G
Dog Lupus familis XP_542314 231 25003 Y57 C E P A G P V Y T S G L R G G
Cat Felis silvestris
Mouse Mus musculus Q9D009 231 24937 Y57 C E P A G P V Y T G G L R G G
Rat Rattus norvegicus NP_001102387 231 25179 Y57 C E P A G P V Y T G G L R G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q29R99 224 24646 T53 C E H E P V Y T I G L R Q A P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VN27 234 26015 T55 Q E H D P V Y T V G L R T K D
Honey Bee Apis mellifera XP_001121995 236 26912 T52 I E H N P V F T V G I R D K I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793736 240 27062 T60 C T H N P V Y T I G I R T K G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SXP7 235 26403 L51 Q H P P T Y T L G K R R T D H
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.4 96.5 88.3 N.A. 84.4 83.1 N.A. N.A. N.A. N.A. 48 N.A. 45.2 42.7 N.A. 44.5
Protein Similarity: 100 79.7 98.2 93 N.A. 89.6 89.6 N.A. N.A. N.A. N.A. 64.5 N.A. 59.4 65.2 N.A. 58.3
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. N.A. N.A. 13.3 N.A. 6.6 6.6 N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. N.A. N.A. 20 N.A. 6.6 6.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 38.7 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 54 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 55 0 0 0 0 0 28 0 0 0 10 0 % A
% Cys: 73 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 0 0 0 0 10 10 10 % D
% Glu: 0 82 0 10 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 55 0 0 0 10 55 55 0 0 55 64 % G
% His: 0 10 37 0 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 10 0 0 0 0 0 0 0 19 0 19 0 0 0 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 10 0 0 0 28 0 % K
% Leu: 0 0 0 0 0 0 0 10 0 0 19 55 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 19 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 64 10 37 55 0 0 0 0 0 0 0 0 10 % P
% Gln: 19 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 10 46 55 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % S
% Thr: 0 10 0 0 10 0 10 37 55 0 0 0 28 0 0 % T
% Val: 0 0 0 0 0 37 55 0 19 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 28 55 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _