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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC22A20
All Species:
1.52
Human Site:
S538
Identified Species:
3.33
UniProt:
A6NK97
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NK97
NP_001004326.3
555
60459
S538
K
K
H
V
E
E
K
S
E
E
I
S
L
Q
Q
Chimpanzee
Pan troglodytes
XP_001169267
524
57113
E508
L
A
V
C
F
L
T
E
T
R
N
M
P
L
V
Rhesus Macaque
Macaca mulatta
XP_001115870
550
60174
E532
K
Q
T
P
Q
Q
Q
E
H
Q
K
Y
M
V
P
Dog
Lupus familis
XP_854865
524
57401
E508
L
A
V
C
F
L
A
E
T
R
N
A
P
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q80UJ1
556
60926
K538
S
K
R
D
T
E
Q
K
S
E
E
I
S
L
Q
Rat
Rattus norvegicus
O35956
551
60748
E533
K
Q
N
Q
Q
Q
Q
E
Q
Q
K
Q
M
M
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507099
556
61556
S536
D
V
E
G
W
K
S
S
R
Q
Q
R
L
Q
D
Chicken
Gallus gallus
Frog
Xenopus laevis
Q66J54
558
62434
V541
E
N
E
M
N
E
I
V
S
L
K
K
K
E
G
Zebra Danio
Brachydanio rerio
Q6NYN7
560
61953
L544
S
K
R
L
P
E
K
L
D
L
A
M
K
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCA2
548
60985
A531
K
P
A
P
Q
E
T
A
E
E
G
G
T
Q
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U539
585
65444
A557
D
S
G
M
F
T
Q
A
A
K
K
R
E
S
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.5
46.8
82.3
N.A.
85.2
45.4
N.A.
40.2
N.A.
47.6
48
N.A.
31.1
N.A.
25.1
N.A.
Protein Similarity:
100
92.2
62.8
87
N.A.
91.7
63.2
N.A.
61.5
N.A.
66.8
65.8
N.A.
50.4
N.A.
45.9
N.A.
P-Site Identity:
100
0
6.6
0
N.A.
26.6
6.6
N.A.
20
N.A.
6.6
20
N.A.
33.3
N.A.
6.6
N.A.
P-Site Similarity:
100
0
46.6
6.6
N.A.
33.3
60
N.A.
33.3
N.A.
26.6
33.3
N.A.
53.3
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
10
0
0
0
10
19
10
0
10
10
0
0
0
% A
% Cys:
0
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
0
0
10
0
0
0
0
10
0
0
0
0
10
10
% D
% Glu:
10
0
19
0
10
46
0
37
19
28
10
0
10
10
10
% E
% Phe:
0
0
0
0
28
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
10
0
0
0
0
0
0
10
10
0
0
10
% G
% His:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
10
10
0
0
0
% I
% Lys:
37
28
0
0
0
10
19
10
0
10
37
10
19
0
0
% K
% Leu:
19
0
0
10
0
19
0
10
0
19
0
0
19
28
0
% L
% Met:
0
0
0
19
0
0
0
0
0
0
0
19
19
10
0
% M
% Asn:
0
10
10
0
10
0
0
0
0
0
19
0
0
0
0
% N
% Pro:
0
10
0
19
10
0
0
0
0
0
0
0
19
0
28
% P
% Gln:
0
19
0
10
28
19
37
0
10
28
10
10
0
28
28
% Q
% Arg:
0
0
19
0
0
0
0
0
10
19
0
19
0
0
0
% R
% Ser:
19
10
0
0
0
0
10
19
19
0
0
10
10
10
0
% S
% Thr:
0
0
10
0
10
10
19
0
19
0
0
0
10
0
0
% T
% Val:
0
10
19
10
0
0
0
10
0
0
0
0
0
10
19
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _