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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC22A20 All Species: 10.91
Human Site: Y393 Identified Species: 24
UniProt: A6NK97 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NK97 NP_001004326.3 555 60459 Y393 V A T A T M I Y V G R R A T V
Chimpanzee Pan troglodytes XP_001169267 524 57113 L367 M D L Q K F G L S L Y L V Q A
Rhesus Macaque Macaca mulatta XP_001115870 550 60174 S391 V G F L V I N S L G R R P A Q
Dog Lupus familis XP_854865 524 57401 L367 M D L Q K F G L S V Y L V Q V
Cat Felis silvestris
Mouse Mus musculus Q80UJ1 556 60926 Y393 V A T T T M I Y V G R R A T V
Rat Rattus norvegicus O35956 551 60748 S391 V C F L V I N S M G R R P A Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507099 556 61556 K393 G S V D F L A K L M A Y I F L
Chicken Gallus gallus
Frog Xenopus laevis Q66J54 558 62434 Y396 F S T T A M I Y V G R K F T Q
Zebra Danio Brachydanio rerio Q6NYN7 560 61953 M399 I V T I C M S M L G R R P S Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VCA2 548 60985 R390 L L L F T L N R W G R R S I L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9U539 585 65444 C412 V V W P L L Q C A G R R W T L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.5 46.8 82.3 N.A. 85.2 45.4 N.A. 40.2 N.A. 47.6 48 N.A. 31.1 N.A. 25.1 N.A.
Protein Similarity: 100 92.2 62.8 87 N.A. 91.7 63.2 N.A. 61.5 N.A. 66.8 65.8 N.A. 50.4 N.A. 45.9 N.A.
P-Site Identity: 100 0 26.6 6.6 N.A. 93.3 26.6 N.A. 0 N.A. 53.3 33.3 N.A. 26.6 N.A. 33.3 N.A.
P-Site Similarity: 100 6.6 40 13.3 N.A. 93.3 40 N.A. 26.6 N.A. 66.6 53.3 N.A. 53.3 N.A. 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 0 10 10 0 10 0 10 0 10 0 19 19 10 % A
% Cys: 0 10 0 0 10 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 19 0 10 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 10 0 19 10 10 19 0 0 0 0 0 0 10 10 0 % F
% Gly: 10 10 0 0 0 0 19 0 0 73 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 10 0 19 28 0 0 0 0 0 10 10 0 % I
% Lys: 0 0 0 0 19 0 0 10 0 0 0 10 0 0 0 % K
% Leu: 10 10 28 19 10 28 0 19 28 10 0 19 0 0 28 % L
% Met: 19 0 0 0 0 37 0 10 10 10 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 28 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 10 0 0 0 0 0 0 0 0 28 0 0 % P
% Gln: 0 0 0 19 0 0 10 0 0 0 0 0 0 19 37 % Q
% Arg: 0 0 0 0 0 0 0 10 0 0 73 64 0 0 0 % R
% Ser: 0 19 0 0 0 0 10 19 19 0 0 0 10 10 0 % S
% Thr: 0 0 37 19 28 0 0 0 0 0 0 0 0 37 0 % T
% Val: 46 19 10 0 19 0 0 0 28 10 0 0 19 0 28 % V
% Trp: 0 0 10 0 0 0 0 0 10 0 0 0 10 0 0 % W
% Tyr: 0 0 0 0 0 0 0 28 0 0 19 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _