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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC85C All Species: 8.18
Human Site: S339 Identified Species: 20
UniProt: A6NKD9 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NKD9 NP_001138467.1 419 45210 S339 P E L P S P P S A G Y S P A G
Chimpanzee Pan troglodytes XP_001152325 360 38678 S280 P E L P S P P S A G Y S P A G
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_855306 149 15874 H92 A M K V L E V H E N L D R Q L
Cat Felis silvestris
Mouse Mus musculus Q5SP85 500 54465 E355 R A R G T S P E H L K Q H Y G
Rat Rattus norvegicus XP_001076332 420 45343 S340 P E L P S P P S T V Y S S A G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515266 154 18430 K96 F L D D D R Q K G R R V G R E
Chicken Gallus gallus XP_421357 392 44299 A313 D L A S S P A A G Y V P V G Q
Frog Xenopus laevis Q4V872 390 43971 A311 E V S S T A P A G Y I P V V Q
Zebra Danio Brachydanio rerio Q6DHL7 399 45075 G321 S E S S P S T G F I S S A Q K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001193795 394 44088 N297 L E R D T T P N H L E N D H M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.9 N.A. 29.8 N.A. 37.7 93.3 N.A. 29.1 72.3 69.6 63 N.A. N.A. N.A. N.A. 26.2
Protein Similarity: 100 85.9 N.A. 32.4 N.A. 49.4 95.2 N.A. 33.1 81.3 79.7 75.6 N.A. N.A. N.A. N.A. 42.2
P-Site Identity: 100 100 N.A. 0 N.A. 13.3 80 N.A. 0 13.3 6.6 13.3 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 N.A. 0 N.A. 20 80 N.A. 0 20 20 13.3 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 10 0 0 10 10 20 20 0 0 0 10 30 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 10 20 10 0 0 0 0 0 0 10 10 0 0 % D
% Glu: 10 50 0 0 0 10 0 10 10 0 10 0 0 0 10 % E
% Phe: 10 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 0 0 10 30 20 0 0 10 10 40 % G
% His: 0 0 0 0 0 0 0 10 20 0 0 0 10 10 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 0 % I
% Lys: 0 0 10 0 0 0 0 10 0 0 10 0 0 0 10 % K
% Leu: 10 20 30 0 10 0 0 0 0 20 10 0 0 0 10 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 0 0 10 0 10 0 10 0 0 0 % N
% Pro: 30 0 0 30 10 40 60 0 0 0 0 20 20 0 0 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 0 10 0 20 20 % Q
% Arg: 10 0 20 0 0 10 0 0 0 10 10 0 10 10 0 % R
% Ser: 10 0 20 30 40 20 0 30 0 0 10 40 10 0 0 % S
% Thr: 0 0 0 0 30 10 10 0 10 0 0 0 0 0 0 % T
% Val: 0 10 0 10 0 0 10 0 0 10 10 10 20 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 20 30 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _