KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDR42E2
All Species:
2.12
Human Site:
S376
Identified Species:
3.59
UniProt:
A6NKP2
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NKP2
XP_002343493.1
422
46869
S376
A
V
E
L
Y
V
Q
S
T
T
R
R
P
R
G
Chimpanzee
Pan troglodytes
XP_001148161
393
44225
H353
A
V
E
W
F
K
A
H
G
H
G
R
S
S
G
Rhesus Macaque
Macaca mulatta
P27365
373
41987
V354
E
E
A
K
Q
K
T
V
E
W
V
G
S
L
V
Dog
Lupus familis
XP_546811
393
43999
H353
V
V
D
W
F
K
A
H
G
H
G
R
S
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9D665
394
43876
H354
V
V
E
W
F
K
A
H
G
H
G
R
G
A
A
Rat
Rattus norvegicus
Q5PPL3
362
40393
L341
K
L
I
G
Y
R
P
L
V
T
M
D
D
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506431
386
42884
N350
T
W
P
R
Q
H
S
N
P
G
L
L
K
L
L
Chicken
Gallus gallus
XP_414919
454
50509
T410
S
V
E
H
Y
I
K
T
R
A
E
A
R
S
E
Frog
Xenopus laevis
Q0IH73
386
43592
H350
V
A
E
W
F
K
N
H
G
Y
G
K
Q
D
K
Zebra Danio
Brachydanio rerio
A8DZE7
387
43577
R350
V
V
Q
W
F
Q
A
R
G
H
G
K
K
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781210
379
42410
R345
M
V
Q
Y
F
L
E
R
G
H
R
K
K
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001132313
479
53215
W370
L
A
A
T
I
S
Y
W
Q
E
R
K
R
M
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FX01
439
48106
F358
I
K
R
T
I
D
S
F
S
H
L
K
A
Q
N
Baker's Yeast
Sacchar. cerevisiae
P53199
349
38688
P330
K
K
L
L
G
Y
T
P
R
V
G
I
E
E
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.2
26.5
45.7
N.A.
43.8
26.7
N.A.
57.5
53
43.1
42.8
N.A.
N.A.
N.A.
N.A.
39.1
Protein Similarity:
100
59.9
40.5
60.4
N.A.
59.7
46.4
N.A.
67.5
68.9
58
59
N.A.
N.A.
N.A.
N.A.
56.1
P-Site Identity:
100
33.3
0
20
N.A.
20
13.3
N.A.
0
20
6.6
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
40
0
33.3
N.A.
26.6
20
N.A.
6.6
46.6
20
33.3
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
34
N.A.
28.4
25.3
N.A.
Protein Similarity:
N.A.
48.6
N.A.
47.8
40.5
N.A.
P-Site Identity:
N.A.
6.6
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
15
15
0
0
0
29
0
0
8
0
8
8
15
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
8
0
0
0
0
0
8
8
8
0
% D
% Glu:
8
8
36
0
0
0
8
0
8
8
8
0
8
8
15
% E
% Phe:
0
0
0
0
43
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
8
0
0
0
43
8
43
8
8
0
29
% G
% His:
0
0
0
8
0
8
0
29
0
43
0
0
0
0
0
% H
% Ile:
8
0
8
0
15
8
0
0
0
0
0
8
0
0
0
% I
% Lys:
15
15
0
8
0
36
8
0
0
0
0
36
22
0
8
% K
% Leu:
8
8
8
15
0
8
0
8
0
0
15
8
0
15
8
% L
% Met:
8
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
8
% N
% Pro:
0
0
8
0
0
0
8
8
8
0
0
0
8
0
0
% P
% Gln:
0
0
15
0
15
8
8
0
8
0
0
0
8
8
0
% Q
% Arg:
0
0
8
8
0
8
0
15
15
0
22
29
15
15
0
% R
% Ser:
8
0
0
0
0
8
15
8
8
0
0
0
22
29
15
% S
% Thr:
8
0
0
15
0
0
15
8
8
15
0
0
0
0
0
% T
% Val:
29
50
0
0
0
8
0
8
8
8
8
0
0
0
15
% V
% Trp:
0
8
0
36
0
0
0
8
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
8
22
8
8
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _