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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SDR42E2 All Species: 17.58
Human Site: Y143 Identified Species: 29.74
UniProt: A6NKP2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NKP2 XP_002343493.1 422 46869 Y143 R R V P R L I Y T S T V N V A
Chimpanzee Pan troglodytes XP_001148161 393 44225 H148 P Y L P L H L H P D H Y S R T
Rhesus Macaque Macaca mulatta P27365 373 41987 K160 A P Y P Y S K K L A E K A V L
Dog Lupus familis XP_546811 393 43999 Y152 L H L H P D H Y S R T K S I A
Cat Felis silvestris
Mouse Mus musculus Q9D665 394 43876 Y153 L H L H P D H Y S R T K S I A
Rat Rattus norvegicus Q5PPL3 362 40393 D143 S V V F E G V D I K N G T E D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506431 386 42884 Y149 R C V P R L V Y T S T V N V A
Chicken Gallus gallus XP_414919 454 50509 Y177 R N I T R L I Y T S T V N V V
Frog Xenopus laevis Q0IH73 386 43592 P142 D E S L P Y L P Q D A F V D N
Zebra Danio Brachydanio rerio A8DZE7 387 43577 Y149 L H L H P D H Y S R T K S I A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781210 379 42410 Y150 L S A H K D D Y S R T K S M A
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001132313 479 53215 V169 K S V A E Q L V L K S N G R P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FX01 439 48106 Y153 N A D E S L P Y P P K H N D S
Baker's Yeast Sacchar. cerevisiae P53199 349 38688 A137 N G Q D V H N A D E T W P I P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.2 26.5 45.7 N.A. 43.8 26.7 N.A. 57.5 53 43.1 42.8 N.A. N.A. N.A. N.A. 39.1
Protein Similarity: 100 59.9 40.5 60.4 N.A. 59.7 46.4 N.A. 67.5 68.9 58 59 N.A. N.A. N.A. N.A. 56.1
P-Site Identity: 100 6.6 13.3 20 N.A. 20 6.6 N.A. 86.6 73.3 0 20 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 33.3 20 46.6 N.A. 46.6 13.3 N.A. 93.3 80 6.6 46.6 N.A. N.A. N.A. N.A. 46.6
Percent
Protein Identity: N.A. 34 N.A. 28.4 25.3 N.A.
Protein Similarity: N.A. 48.6 N.A. 47.8 40.5 N.A.
P-Site Identity: N.A. 6.6 N.A. 20 6.6 N.A.
P-Site Similarity: N.A. 26.6 N.A. 26.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 8 0 0 0 8 0 8 8 0 8 0 43 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 8 8 0 29 8 8 8 15 0 0 0 15 8 % D
% Glu: 0 8 0 8 15 0 0 0 0 8 8 0 0 8 0 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 0 8 0 0 0 8 0 0 0 0 0 8 8 0 0 % G
% His: 0 22 0 29 0 15 22 8 0 0 8 8 0 0 0 % H
% Ile: 0 0 8 0 0 0 15 0 8 0 0 0 0 29 0 % I
% Lys: 8 0 0 0 8 0 8 8 0 15 8 36 0 0 0 % K
% Leu: 29 0 29 8 8 29 22 0 15 0 0 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 15 8 0 0 0 0 8 0 0 0 8 8 29 0 8 % N
% Pro: 8 8 0 29 29 0 8 8 15 8 0 0 8 0 15 % P
% Gln: 0 0 8 0 0 8 0 0 8 0 0 0 0 0 0 % Q
% Arg: 22 8 0 0 22 0 0 0 0 29 0 0 0 15 0 % R
% Ser: 8 15 8 0 8 8 0 0 29 22 8 0 36 0 8 % S
% Thr: 0 0 0 8 0 0 0 0 22 0 58 0 8 0 8 % T
% Val: 0 8 29 0 8 0 15 8 0 0 0 22 8 29 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 0 8 8 0 8 8 0 58 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _