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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SDR42E2 All Species: 2.12
Human Site: Y276 Identified Species: 3.59
UniProt: A6NKP2 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NKP2 XP_002343493.1 422 46869 Y276 V A S G Q A Y Y I N D G E S V
Chimpanzee Pan troglodytes XP_001148161 393 44225 F253 I A S G Q P Y F I S D G R P V
Rhesus Macaque Macaca mulatta P27365 373 41987 Y255 S V Q G Q F Y Y I S D D T P H
Dog Lupus familis XP_546811 393 43999 F253 I A S G Q P Y F I S D G R P V
Cat Felis silvestris
Mouse Mus musculus Q9D665 394 43876 F254 V A S G Q P Y F I S D G R P V
Rat Rattus norvegicus Q5PPL3 362 40393 H242 G H I L A A E H L S R D A G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506431 386 42884 Q249 R F G D P T A Q M N W V H V H
Chicken Gallus gallus XP_414919 454 50509 F310 I A S G Q V Y F I H D G E K F
Frog Xenopus laevis Q0IH73 386 43592 F250 I A A G Q P Y F I S D G P P V
Zebra Danio Brachydanio rerio A8DZE7 387 43577 F250 R A A G Q A Y F I S D G R P V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781210 379 42410 F245 I A A G Q V Y F I A D K A P V
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001132313 479 53215 F265 V A A G Q A Y F I C D G S P C
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FX01 439 48106 F258 K A A G Q A Y F I T N M E P I
Baker's Yeast Sacchar. cerevisiae P53199 349 38688 K232 A H V L A A Q K L L D P K T R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.2 26.5 45.7 N.A. 43.8 26.7 N.A. 57.5 53 43.1 42.8 N.A. N.A. N.A. N.A. 39.1
Protein Similarity: 100 59.9 40.5 60.4 N.A. 59.7 46.4 N.A. 67.5 68.9 58 59 N.A. N.A. N.A. N.A. 56.1
P-Site Identity: 100 60 40 60 N.A. 66.6 6.6 N.A. 6.6 60 53.3 60 N.A. N.A. N.A. N.A. 46.6
P-Site Similarity: 100 80 46.6 80 N.A. 80 33.3 N.A. 13.3 80 80 80 N.A. N.A. N.A. N.A. 66.6
Percent
Protein Identity: N.A. 34 N.A. 28.4 25.3 N.A.
Protein Similarity: N.A. 48.6 N.A. 47.8 40.5 N.A.
P-Site Identity: N.A. 60 N.A. 46.6 13.3 N.A.
P-Site Similarity: N.A. 73.3 N.A. 73.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 72 36 0 15 43 8 0 0 8 0 0 15 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 8 % C
% Asp: 0 0 0 8 0 0 0 0 0 0 79 15 0 0 0 % D
% Glu: 0 0 0 0 0 0 8 0 0 0 0 0 22 0 0 % E
% Phe: 0 8 0 0 0 8 0 65 0 0 0 0 0 0 8 % F
% Gly: 8 0 8 79 0 0 0 0 0 0 0 58 0 8 0 % G
% His: 0 15 0 0 0 0 0 8 0 8 0 0 8 0 15 % H
% Ile: 36 0 8 0 0 0 0 0 79 0 0 0 0 0 8 % I
% Lys: 8 0 0 0 0 0 0 8 0 0 0 8 8 8 0 % K
% Leu: 0 0 0 15 0 0 0 0 15 8 0 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 8 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 15 8 0 0 0 0 % N
% Pro: 0 0 0 0 8 29 0 0 0 0 0 8 8 65 0 % P
% Gln: 0 0 8 0 79 0 8 8 0 0 0 0 0 0 0 % Q
% Arg: 15 0 0 0 0 0 0 0 0 0 8 0 29 0 8 % R
% Ser: 8 0 36 0 0 0 0 0 0 50 0 0 8 8 0 % S
% Thr: 0 0 0 0 0 8 0 0 0 8 0 0 8 8 0 % T
% Val: 22 8 8 0 0 15 0 0 0 0 0 8 0 8 50 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 79 15 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _