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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
All Species:
6.97
Human Site:
S109
Identified Species:
13.94
UniProt:
A6NKX4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NKX4
XP_370997.4
558
58987
S109
P
R
P
S
S
W
A
S
C
S
G
A
A
A
G
Chimpanzee
Pan troglodytes
XP_523468
559
58946
S112
P
R
P
S
S
W
A
S
C
S
G
A
A
A
G
Rhesus Macaque
Macaca mulatta
XP_001101737
572
60759
N109
P
R
P
V
P
A
P
N
G
T
R
P
C
T
R
Dog
Lupus familis
XP_851018
588
62602
V108
A
A
S
W
L
P
C
V
A
L
G
L
A
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3UHH2
689
74306
T204
A
W
D
Y
G
I
R
T
G
L
I
Q
N
V
V
Rat
Rattus norvegicus
Q9P290
516
55377
I87
P
V
L
T
T
N
A
I
G
Q
W
D
L
V
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511561
613
65361
R112
R
T
P
R
A
I
L
R
A
G
T
L
H
R
S
Chicken
Gallus gallus
XP_418968
691
75063
A214
E
W
H
Y
R
I
R
A
G
L
V
Q
N
V
V
Frog
Xenopus laevis
Q66J54
558
62434
A106
W
A
N
S
S
Q
L
A
T
R
P
C
T
E
G
Zebra Danio
Brachydanio rerio
Q6NYN7
560
61953
T122
D
G
W
F
Y
N
M
T
E
M
S
S
T
I
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCA2
548
60985
S110
S
S
Y
V
Y
D
R
S
K
Y
L
N
S
A
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U539
585
65444
S134
N
G
W
D
Y
D
N
S
T
Y
L
D
S
L
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
85.8
61.7
N.A.
31
34.9
N.A.
42
29.6
25.2
23.9
N.A.
24.9
N.A.
21.3
N.A.
Protein Similarity:
100
97.5
88.6
66.8
N.A.
45.7
48.9
N.A.
53.3
44.4
42.4
41.7
N.A.
40.8
N.A.
39.1
N.A.
P-Site Identity:
100
100
20
20
N.A.
0
13.3
N.A.
6.6
0
20
0
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
100
33.3
20
N.A.
6.6
26.6
N.A.
13.3
6.6
26.6
13.3
N.A.
20
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
17
0
0
9
9
25
17
17
0
0
17
25
25
0
% A
% Cys:
0
0
0
0
0
0
9
0
17
0
0
9
9
0
9
% C
% Asp:
9
0
9
9
0
17
0
0
0
0
0
17
0
0
0
% D
% Glu:
9
0
0
0
0
0
0
0
9
0
0
0
0
9
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
17
0
0
9
0
0
0
34
9
25
0
0
0
34
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
0
25
0
9
0
0
9
0
0
9
9
% I
% Lys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% K
% Leu:
0
0
9
0
9
0
17
0
0
25
17
17
9
17
0
% L
% Met:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% M
% Asn:
9
0
9
0
0
17
9
9
0
0
0
9
17
0
0
% N
% Pro:
34
0
34
0
9
9
9
0
0
0
9
9
0
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
0
9
0
17
0
0
0
% Q
% Arg:
9
25
0
9
9
0
25
9
0
9
9
0
0
9
9
% R
% Ser:
9
9
9
25
25
0
0
34
0
17
9
9
17
0
9
% S
% Thr:
0
9
0
9
9
0
0
17
17
9
9
0
17
9
0
% T
% Val:
0
9
0
17
0
0
0
9
0
0
9
0
0
25
34
% V
% Trp:
9
17
17
9
0
17
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
9
17
25
0
0
0
0
17
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _