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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AQP12B
All Species:
1.21
Human Site:
S280
Identified Species:
2.67
UniProt:
A6NM10
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NM10
NP_001095937.1
295
31475
S280
Q
T
P
A
K
G
S
S
V
R
E
P
G
R
S
Chimpanzee
Pan troglodytes
XP_001175046
271
30109
F257
M
I
L
M
F
S
F
F
L
P
W
L
H
N
N
Rhesus Macaque
Macaca mulatta
XP_001090652
271
30269
F257
M
I
L
M
F
S
F
F
L
P
W
L
H
N
N
Dog
Lupus familis
XP_534003
272
30635
F258
M
I
L
M
F
S
F
F
L
P
W
L
Y
N
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHJ2
290
31271
R274
K
S
K
Y
R
T
P
R
G
K
L
S
P
G
S
Rat
Rattus norvegicus
Q8CHM1
271
30351
F257
M
I
L
M
F
S
F
F
L
P
W
L
H
N
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507166
204
21427
T190
P
A
G
K
Q
E
K
T
R
K
K
R
A
G
G
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088119
320
35096
P292
A
S
D
N
L
K
S
P
Q
K
R
K
A
P
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001163140
266
29015
R252
F
K
V
P
A
V
R
R
L
L
L
G
E
G
A
Honey Bee
Apis mellifera
XP_001119956
269
30183
P255
S
L
R
V
Y
K
S
P
F
V
Q
Q
Y
M
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780933
267
29544
A253
L
A
R
A
I
A
G
A
F
N
R
P
T
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.7
27.4
27.7
N.A.
70.8
27.1
N.A.
33.9
N.A.
47.5
N.A.
N.A.
25.4
20.3
N.A.
27.8
Protein Similarity:
100
42
41.6
41.6
N.A.
77.2
44.4
N.A.
44.4
N.A.
63.1
N.A.
N.A.
44
37.2
N.A.
42
P-Site Identity:
100
0
0
0
N.A.
6.6
0
N.A.
0
N.A.
6.6
N.A.
N.A.
0
6.6
N.A.
13.3
P-Site Similarity:
100
13.3
13.3
6.6
N.A.
33.3
13.3
N.A.
26.6
N.A.
20
N.A.
N.A.
13.3
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
19
0
19
10
10
0
10
0
0
0
0
19
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
0
10
0
10
0
19
% E
% Phe:
10
0
0
0
37
0
37
37
19
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
10
10
0
10
0
0
10
10
28
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
28
0
10
% H
% Ile:
0
37
0
0
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
10
10
10
10
19
10
0
0
28
10
10
0
0
0
% K
% Leu:
10
10
37
0
10
0
0
0
46
10
19
37
0
0
0
% L
% Met:
37
0
0
37
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
10
0
0
0
37
28
% N
% Pro:
10
0
10
10
0
0
10
19
0
37
0
19
10
19
0
% P
% Gln:
10
0
0
0
10
0
0
0
10
0
10
10
0
0
0
% Q
% Arg:
0
0
19
0
10
0
10
19
10
10
19
10
0
10
0
% R
% Ser:
10
19
0
0
0
37
28
10
0
0
0
10
0
0
19
% S
% Thr:
0
10
0
0
0
10
0
10
0
0
0
0
10
0
0
% T
% Val:
0
0
10
10
0
10
0
0
10
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
37
0
0
0
0
% W
% Tyr:
0
0
0
10
10
0
0
0
0
0
0
0
19
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _