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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIGLEC16
All Species:
10.91
Human Site:
S461
Identified Species:
40
UniProt:
A6NMB1
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NMB1
NP_001128635
481
52992
S461
L
I
L
L
R
V
R
S
C
R
R
K
A
A
R
Chimpanzee
Pan troglodytes
Q95LH0
597
65057
S506
I
I
F
V
V
V
R
S
C
R
K
K
S
A
R
Rhesus Macaque
Macaca mulatta
XP_001115790
590
64077
T478
L
V
I
F
G
V
K
T
C
R
K
E
A
R
K
Dog
Lupus familis
XP_863221
605
67368
R479
L
L
V
M
K
I
L
R
K
K
Q
T
Q
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q91Y57
467
51871
T452
L
W
G
Q
Q
D
T
T
T
E
Y
S
E
I
K
Rat
Rattus norvegicus
P07722
626
69334
T536
I
V
C
Y
I
T
Q
T
R
R
K
K
N
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518834
575
63465
D488
M
L
K
K
K
G
G
D
S
K
T
E
V
S
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.8
65.4
50.2
N.A.
34.9
21.4
N.A.
31.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
46.7
71.6
61.8
N.A.
49.9
36
N.A.
46
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
60
33.3
13.3
N.A.
6.6
13.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
80
60
N.A.
26.6
46.6
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
29
43
0
% A
% Cys:
0
0
15
0
0
0
0
0
43
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
15
0
15
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
15
0
29
15
0
0
% E
% Phe:
0
0
15
15
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
15
0
15
15
15
0
0
0
0
0
0
0
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
29
29
15
0
15
15
0
0
0
0
0
0
0
15
0
% I
% Lys:
0
0
15
15
29
0
15
0
15
29
43
43
0
0
43
% K
% Leu:
58
29
15
15
0
0
15
0
0
0
0
0
0
0
0
% L
% Met:
15
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
15
15
0
15
0
0
0
15
0
15
0
0
% Q
% Arg:
0
0
0
0
15
0
29
15
15
58
15
0
0
15
29
% R
% Ser:
0
0
0
0
0
0
0
29
15
0
0
15
15
15
0
% S
% Thr:
0
0
0
0
0
15
15
43
15
0
15
15
0
0
15
% T
% Val:
0
29
15
15
15
43
0
0
0
0
0
0
15
15
0
% V
% Trp:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
15
0
0
0
0
0
0
15
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _