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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SIGLEC16 All Species: 10.91
Human Site: S461 Identified Species: 40
UniProt: A6NMB1 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NMB1 NP_001128635 481 52992 S461 L I L L R V R S C R R K A A R
Chimpanzee Pan troglodytes Q95LH0 597 65057 S506 I I F V V V R S C R K K S A R
Rhesus Macaque Macaca mulatta XP_001115790 590 64077 T478 L V I F G V K T C R K E A R K
Dog Lupus familis XP_863221 605 67368 R479 L L V M K I L R K K Q T Q A G
Cat Felis silvestris
Mouse Mus musculus Q91Y57 467 51871 T452 L W G Q Q D T T T E Y S E I K
Rat Rattus norvegicus P07722 626 69334 T536 I V C Y I T Q T R R K K N V T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518834 575 63465 D488 M L K K K G G D S K T E V S K
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 33.8 65.4 50.2 N.A. 34.9 21.4 N.A. 31.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 46.7 71.6 61.8 N.A. 49.9 36 N.A. 46 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 60 33.3 13.3 N.A. 6.6 13.3 N.A. 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 86.6 80 60 N.A. 26.6 46.6 N.A. 46.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 29 43 0 % A
% Cys: 0 0 15 0 0 0 0 0 43 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 15 0 15 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 15 0 29 15 0 0 % E
% Phe: 0 0 15 15 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 15 0 15 15 15 0 0 0 0 0 0 0 15 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 29 29 15 0 15 15 0 0 0 0 0 0 0 15 0 % I
% Lys: 0 0 15 15 29 0 15 0 15 29 43 43 0 0 43 % K
% Leu: 58 29 15 15 0 0 15 0 0 0 0 0 0 0 0 % L
% Met: 15 0 0 15 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 15 15 0 15 0 0 0 15 0 15 0 0 % Q
% Arg: 0 0 0 0 15 0 29 15 15 58 15 0 0 15 29 % R
% Ser: 0 0 0 0 0 0 0 29 15 0 0 15 15 15 0 % S
% Thr: 0 0 0 0 0 15 15 43 15 0 15 15 0 0 15 % T
% Val: 0 29 15 15 15 43 0 0 0 0 0 0 15 15 0 % V
% Trp: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 15 0 0 0 0 0 0 15 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _