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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF4E1B
All Species:
21.82
Human Site:
S108
Identified Species:
30
UniProt:
A6NMX2
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NMX2
NP_001092878.1
242
27596
S108
Y
S
H
I
Q
L
A
S
K
L
S
S
G
C
D
Chimpanzee
Pan troglodytes
XP_518121
188
21714
S58
Q
L
A
S
K
L
S
S
G
C
D
Y
A
L
F
Rhesus Macaque
Macaca mulatta
XP_001092045
253
28850
S119
Y
S
H
I
Q
L
A
S
K
L
S
S
G
C
D
Dog
Lupus familis
XP_546215
202
23200
S72
Q
L
A
S
K
L
S
S
G
C
D
Y
A
L
F
Cat
Felis silvestris
Mouse
Mus musculus
Q3UTA9
244
27967
S111
Y
S
H
I
K
L
A
S
K
L
S
S
G
C
D
Rat
Rattus norvegicus
P63074
217
25035
P87
Q
L
S
S
N
L
M
P
G
C
D
Y
S
L
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519751
214
24578
P84
Q
P
A
S
K
L
T
P
G
C
D
Y
S
L
F
Chicken
Gallus gallus
XP_420655
217
25026
P87
Q
L
S
S
N
L
M
P
G
C
D
Y
S
L
F
Frog
Xenopus laevis
P48597
213
24616
S83
Q
L
S
S
N
L
M
S
G
C
D
Y
S
L
F
Zebra Danio
Brachydanio rerio
Q9DFS6
215
24831
S85
Q
L
S
S
N
L
M
S
G
C
D
Y
S
L
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48598
259
29205
S127
Y
N
H
I
K
P
P
S
E
I
K
L
G
S
D
Honey Bee
Apis mellifera
XP_624290
213
24784
Q83
K
A
A
S
E
L
K
Q
G
C
D
Y
S
M
F
Nematode Worm
Caenorhab. elegans
O61955
248
27791
K114
R
W
L
V
V
V
D
K
Q
R
R
T
Q
L
L
Sea Urchin
Strong. purpuratus
NP_001091928
225
25645
S91
Y
N
H
I
Q
V
A
S
R
I
T
S
G
C
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O81481
218
24452
I88
F
W
G
L
Y
N
N
I
N
H
P
S
K
L
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O23252
235
26501
S100
S
T
V
E
E
F
W
S
L
Y
N
N
M
K
H
Baker's Yeast
Sacchar. cerevisiae
P07260
213
24236
E83
A
I
I
Q
N
I
P
E
P
H
E
L
P
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.8
90.5
74.7
N.A.
67.6
60.7
N.A.
61.5
61.9
61.5
61.5
N.A.
39
47.1
41.9
46.6
Protein Similarity:
100
77.6
93.2
78
N.A.
79
71.9
N.A.
73.1
73.9
72.7
73.9
N.A.
57.9
63.2
58.4
68.6
P-Site Identity:
100
13.3
100
13.3
N.A.
93.3
6.6
N.A.
6.6
6.6
13.3
13.3
N.A.
40
6.6
0
66.6
P-Site Similarity:
100
26.6
100
26.6
N.A.
100
6.6
N.A.
13.3
6.6
13.3
13.3
N.A.
66.6
20
26.6
100
Percent
Protein Identity:
N.A.
33
N.A.
35.1
31.4
N.A.
Protein Similarity:
N.A.
48.7
N.A.
53.3
53.7
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
20
N.A.
33.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
6
24
0
0
0
24
0
0
0
0
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
48
0
0
0
24
0
% C
% Asp:
0
0
0
0
0
0
6
0
0
0
48
0
0
0
30
% D
% Glu:
0
0
0
6
12
0
0
6
6
0
6
0
0
0
0
% E
% Phe:
6
0
0
0
0
6
0
0
0
0
0
0
0
0
48
% F
% Gly:
0
0
6
0
0
0
0
0
48
0
0
0
30
0
0
% G
% His:
0
0
30
0
0
0
0
0
0
12
0
0
0
0
6
% H
% Ile:
0
6
6
30
0
6
0
6
0
12
0
0
0
0
6
% I
% Lys:
6
0
0
0
30
0
6
6
18
0
6
0
6
6
6
% K
% Leu:
0
36
6
6
0
65
0
0
6
18
0
12
0
59
6
% L
% Met:
0
0
0
0
0
0
24
0
0
0
0
0
6
6
0
% M
% Asn:
0
12
0
0
30
6
6
0
6
0
6
6
0
0
0
% N
% Pro:
0
6
0
0
0
6
12
18
6
0
6
0
6
0
0
% P
% Gln:
42
0
0
6
18
0
0
6
6
0
0
0
6
0
0
% Q
% Arg:
6
0
0
0
0
0
0
0
6
6
6
0
0
0
0
% R
% Ser:
6
18
24
48
0
0
12
59
0
0
18
30
36
6
0
% S
% Thr:
0
6
0
0
0
0
6
0
0
0
6
6
0
0
0
% T
% Val:
0
0
6
6
6
12
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
12
0
0
0
0
6
0
0
0
0
0
0
0
0
% W
% Tyr:
30
0
0
0
6
0
0
0
0
6
0
48
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _