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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF4E1B
All Species:
6.67
Human Site:
S44
Identified Species:
9.17
UniProt:
A6NMX2
Number Species:
16
Phosphosite Substitution
Charge Score:
0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NMX2
NP_001092878.1
242
27596
S44
N
S
P
R
T
L
L
S
L
R
G
K
A
R
T
Chimpanzee
Pan troglodytes
XP_518121
188
21714
Rhesus Macaque
Macaca mulatta
XP_001092045
253
28850
S55
N
S
P
R
T
L
L
S
L
R
G
K
A
R
M
Dog
Lupus familis
XP_546215
202
23200
E20
G
P
P
G
V
K
L
E
L
H
P
L
L
N
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3UTA9
244
27967
T47
D
L
P
G
S
L
K
T
Q
R
R
K
A
H
R
Rat
Rattus norvegicus
P63074
217
25035
I35
V
A
N
P
E
H
Y
I
K
H
P
L
Q
N
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519751
214
24578
E32
G
L
V
F
E
M
V
E
K
H
P
L
Q
N
R
Chicken
Gallus gallus
XP_420655
217
25026
I35
V
A
S
P
E
Q
Y
I
K
H
P
L
Q
N
R
Frog
Xenopus laevis
P48597
213
24616
I31
I
V
S
P
D
Q
Y
I
K
H
P
L
Q
N
R
Zebra Danio
Brachydanio rerio
Q9DFS6
215
24831
I33
I
V
S
L
E
D
Y
I
K
H
P
L
Q
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48598
259
29205
P67
N
T
A
T
T
T
A
P
A
G
D
D
A
V
R
Honey Bee
Apis mellifera
XP_624290
213
24784
I31
E
F
P
P
E
V
L
I
K
H
P
L
Q
H
T
Nematode Worm
Caenorhab. elegans
O61955
248
27791
W38
R
H
P
L
Q
N
R
W
A
L
W
Y
L
K
A
Sea Urchin
Strong. purpuratus
NP_001091928
225
25645
D38
D
G
A
N
Q
V
V
D
P
E
S
L
I
K
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O81481
218
24452
A36
E
I
T
D
L
A
C
A
P
S
P
P
A
T
H
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O23252
235
26501
N47
A
G
G
E
G
D
G
N
V
D
E
S
S
K
S
Baker's Yeast
Sacchar. cerevisiae
P07260
213
24236
A31
K
T
V
L
S
D
S
A
H
F
D
V
K
H
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.8
90.5
74.7
N.A.
67.6
60.7
N.A.
61.5
61.9
61.5
61.5
N.A.
39
47.1
41.9
46.6
Protein Similarity:
100
77.6
93.2
78
N.A.
79
71.9
N.A.
73.1
73.9
72.7
73.9
N.A.
57.9
63.2
58.4
68.6
P-Site Identity:
100
0
93.3
20
N.A.
33.3
0
N.A.
0
0
0
0
N.A.
20
20
6.6
0
P-Site Similarity:
100
0
93.3
20
N.A.
53.3
6.6
N.A.
13.3
6.6
0
0
N.A.
26.6
26.6
13.3
26.6
Percent
Protein Identity:
N.A.
33
N.A.
35.1
31.4
N.A.
Protein Similarity:
N.A.
48.7
N.A.
53.3
53.7
N.A.
P-Site Identity:
N.A.
6.6
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
12
12
0
0
6
6
12
12
0
0
0
30
0
6
% A
% Cys:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
0
6
6
18
0
6
0
6
12
6
0
0
0
% D
% Glu:
12
0
0
6
30
0
0
12
0
6
6
0
0
0
0
% E
% Phe:
0
6
0
6
0
0
0
0
0
6
0
0
0
0
0
% F
% Gly:
12
12
6
12
6
0
6
0
0
6
12
0
0
0
0
% G
% His:
0
6
0
0
0
6
0
0
6
42
0
0
0
18
12
% H
% Ile:
12
6
0
0
0
0
0
30
0
0
0
0
6
0
0
% I
% Lys:
6
0
0
0
0
6
6
0
36
0
0
18
6
18
0
% K
% Leu:
0
12
0
18
6
18
24
0
18
6
0
48
12
0
0
% L
% Met:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
6
% M
% Asn:
18
0
6
6
0
6
0
6
0
0
0
0
0
36
0
% N
% Pro:
0
6
36
24
0
0
0
6
12
0
48
6
0
0
6
% P
% Gln:
0
0
0
0
12
12
0
0
6
0
0
0
36
0
0
% Q
% Arg:
6
0
0
12
0
0
6
0
0
18
6
0
0
12
48
% R
% Ser:
0
12
18
0
12
0
6
12
0
6
6
6
6
0
6
% S
% Thr:
0
12
6
6
18
6
0
6
0
0
0
0
0
6
12
% T
% Val:
12
12
12
0
6
12
12
0
6
0
0
6
0
6
0
% V
% Trp:
0
0
0
0
0
0
0
6
0
0
6
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
24
0
0
0
0
6
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _