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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF4E1B
All Species:
15.45
Human Site:
T228
Identified Species:
21.25
UniProt:
A6NMX2
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NMX2
NP_001092878.1
242
27596
T228
G
Y
Q
A
H
A
D
T
A
T
K
S
N
S
L
Chimpanzee
Pan troglodytes
XP_518121
188
21714
A175
Y
Q
A
H
A
D
T
A
T
K
S
N
S
L
A
Rhesus Macaque
Macaca mulatta
XP_001092045
253
28850
T239
G
Y
Q
A
H
A
D
T
A
T
K
S
N
S
L
Dog
Lupus familis
XP_546215
202
23200
A189
Y
Q
A
H
A
D
T
A
T
K
S
N
S
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3UTA9
244
27967
T231
G
Y
Q
A
H
A
D
T
A
A
K
S
N
N
L
Rat
Rattus norvegicus
P63074
217
25035
A204
Y
Q
S
H
A
D
T
A
T
K
S
G
S
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519751
214
24578
A201
Y
Q
A
H
T
D
T
A
S
K
S
H
N
L
T
Chicken
Gallus gallus
XP_420655
217
25026
A204
Y
Q
S
H
A
D
T
A
T
K
S
G
S
T
T
Frog
Xenopus laevis
P48597
213
24616
A200
Y
Q
S
H
A
D
T
A
T
K
S
G
S
T
T
Zebra Danio
Brachydanio rerio
Q9DFS6
215
24831
A202
Y
Q
S
H
A
D
T
A
T
K
S
G
S
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48598
259
29205
T245
Q
Y
Q
L
H
K
D
T
M
V
K
Q
G
S
N
Honey Bee
Apis mellifera
XP_624290
213
24784
M200
Y
Q
I
H
K
D
V
M
V
K
V
G
S
Q
T
Nematode Worm
Caenorhab. elegans
O61955
248
27791
P234
A
T
T
S
P
S
N
P
G
T
E
A
T
G
T
Sea Urchin
Strong. purpuratus
NP_001091928
225
25645
T211
G
Y
E
A
H
K
D
T
M
T
K
T
G
S
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O81481
218
24452
A205
G
F
I
V
H
D
D
A
K
K
M
D
K
G
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O23252
235
26501
D221
I
G
F
I
I
H
E
D
A
K
K
L
D
R
N
Baker's Yeast
Sacchar. cerevisiae
P07260
213
24236
S200
H
L
E
F
F
P
H
S
S
A
N
G
R
H
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.8
90.5
74.7
N.A.
67.6
60.7
N.A.
61.5
61.9
61.5
61.5
N.A.
39
47.1
41.9
46.6
Protein Similarity:
100
77.6
93.2
78
N.A.
79
71.9
N.A.
73.1
73.9
72.7
73.9
N.A.
57.9
63.2
58.4
68.6
P-Site Identity:
100
0
100
0
N.A.
86.6
0
N.A.
6.6
0
0
0
N.A.
46.6
0
6.6
60
P-Site Similarity:
100
13.3
100
13.3
N.A.
93.3
13.3
N.A.
13.3
13.3
13.3
13.3
N.A.
46.6
6.6
40
80
Percent
Protein Identity:
N.A.
33
N.A.
35.1
31.4
N.A.
Protein Similarity:
N.A.
48.7
N.A.
53.3
53.7
N.A.
P-Site Identity:
N.A.
26.6
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
18
24
36
18
0
48
24
12
0
6
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
53
36
6
0
0
0
6
6
0
0
% D
% Glu:
0
0
12
0
0
0
6
0
0
0
6
0
0
0
0
% E
% Phe:
0
6
6
6
6
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
30
6
0
0
0
0
0
0
6
0
0
36
12
12
0
% G
% His:
6
0
0
48
36
6
6
0
0
0
0
6
0
6
0
% H
% Ile:
6
0
12
6
6
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
6
12
0
0
6
59
36
0
6
0
0
% K
% Leu:
0
6
0
6
0
0
0
0
0
0
0
6
0
18
24
% L
% Met:
0
0
0
0
0
0
0
6
12
0
6
0
0
0
6
% M
% Asn:
0
0
0
0
0
0
6
0
0
0
6
12
24
6
12
% N
% Pro:
0
0
0
0
6
6
0
6
0
0
0
0
0
0
6
% P
% Gln:
6
48
24
0
0
0
0
0
0
0
0
6
0
6
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
6
6
0
% R
% Ser:
0
0
24
6
0
6
0
6
12
0
42
18
42
24
0
% S
% Thr:
0
6
6
0
6
0
42
30
36
24
0
6
6
24
42
% T
% Val:
0
0
0
6
0
0
6
0
6
6
6
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
48
30
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _