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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF4E1B
All Species:
6.97
Human Site:
T29
Identified Species:
9.58
UniProt:
A6NMX2
Number Species:
16
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NMX2
NP_001092878.1
242
27596
T29
E
E
E
A
A
E
R
T
P
T
G
E
K
S
P
Chimpanzee
Pan troglodytes
XP_518121
188
21714
Rhesus Macaque
Macaca mulatta
XP_001092045
253
28850
T40
E
E
E
A
A
E
R
T
P
M
G
E
E
V
P
Dog
Lupus familis
XP_546215
202
23200
Cat
Felis silvestris
Mouse
Mus musculus
Q3UTA9
244
27967
G32
P
S
E
A
T
A
E
G
V
Q
A
G
E
A
K
Rat
Rattus norvegicus
P63074
217
25035
E20
N
P
P
P
A
E
E
E
K
T
E
S
N
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519751
214
24578
R17
E
G
P
R
Q
E
Q
R
K
K
K
G
Q
A
K
Chicken
Gallus gallus
XP_420655
217
25026
T20
Q
P
S
E
E
E
K
T
E
P
A
P
T
Q
E
Frog
Xenopus laevis
P48597
213
24616
E16
T
N
P
Q
S
T
E
E
E
K
E
T
G
Q
E
Zebra Danio
Brachydanio rerio
Q9DFS6
215
24831
K18
N
P
S
N
S
E
E
K
N
E
E
N
E
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48598
259
29205
Q52
V
K
P
K
E
D
P
Q
E
T
G
E
P
A
G
Honey Bee
Apis mellifera
XP_624290
213
24784
E16
I
E
E
V
E
R
K
E
Q
E
V
V
N
F
D
Nematode Worm
Caenorhab. elegans
O61955
248
27791
S23
D
V
N
A
S
D
A
S
V
P
P
E
L
L
T
Sea Urchin
Strong. purpuratus
NP_001091928
225
25645
K23
V
K
D
G
K
G
I
K
D
L
Q
T
Q
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O81481
218
24452
E21
S
R
G
R
P
A
P
E
D
D
D
R
E
E
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O23252
235
26501
D32
D
R
Y
H
E
E
G
D
D
A
E
E
G
E
I
Baker's Yeast
Sacchar. cerevisiae
P07260
213
24236
V16
K
F
E
E
N
V
S
V
D
D
T
T
A
T
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.8
90.5
74.7
N.A.
67.6
60.7
N.A.
61.5
61.9
61.5
61.5
N.A.
39
47.1
41.9
46.6
Protein Similarity:
100
77.6
93.2
78
N.A.
79
71.9
N.A.
73.1
73.9
72.7
73.9
N.A.
57.9
63.2
58.4
68.6
P-Site Identity:
100
0
80
0
N.A.
13.3
20
N.A.
13.3
13.3
0
6.6
N.A.
20
13.3
13.3
0
P-Site Similarity:
100
0
86.6
0
N.A.
26.6
20
N.A.
33.3
26.6
6.6
20
N.A.
40
20
40
20
Percent
Protein Identity:
N.A.
33
N.A.
35.1
31.4
N.A.
Protein Similarity:
N.A.
48.7
N.A.
53.3
53.7
N.A.
P-Site Identity:
N.A.
0
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
24
18
12
6
0
0
6
12
0
6
18
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
6
0
0
12
0
6
24
12
6
0
0
6
6
% D
% Glu:
18
18
30
12
24
42
24
24
18
12
24
30
24
12
24
% E
% Phe:
0
6
0
0
0
0
0
0
0
0
0
0
0
6
0
% F
% Gly:
0
6
6
6
0
6
6
6
0
0
18
12
12
0
12
% G
% His:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
6
0
0
0
0
0
6
0
0
0
0
0
0
0
6
% I
% Lys:
6
12
0
6
6
0
12
12
12
12
6
0
6
0
12
% K
% Leu:
0
0
0
0
0
0
0
0
0
6
0
0
6
6
0
% L
% Met:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% M
% Asn:
12
6
6
6
6
0
0
0
6
0
0
6
12
0
0
% N
% Pro:
6
18
24
6
6
0
12
0
12
12
6
6
6
0
18
% P
% Gln:
6
0
0
6
6
0
6
6
6
6
6
0
12
24
6
% Q
% Arg:
0
12
0
12
0
6
12
6
0
0
0
6
0
0
0
% R
% Ser:
6
6
12
0
18
0
6
6
0
0
0
6
0
6
0
% S
% Thr:
6
0
0
0
6
6
0
18
0
18
6
18
6
6
6
% T
% Val:
12
6
0
6
0
6
0
6
12
0
6
6
0
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _