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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF4E1B
All Species:
8.79
Human Site:
Y208
Identified Species:
12.08
UniProt:
A6NMX2
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.56
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NMX2
NP_001092878.1
242
27596
Y208
V
L
H
V
G
R
V
Y
K
E
R
L
G
L
S
Chimpanzee
Pan troglodytes
XP_518121
188
21714
K155
L
H
I
G
R
V
Y
K
E
R
L
G
L
S
P
Rhesus Macaque
Macaca mulatta
XP_001092045
253
28850
Y219
V
L
H
I
G
R
V
Y
K
E
R
L
G
L
S
Dog
Lupus familis
XP_546215
202
23200
K169
L
H
I
G
R
V
Y
K
E
R
L
G
L
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q3UTA9
244
27967
Y211
V
M
Q
I
G
Q
I
Y
K
E
R
L
G
I
S
Rat
Rattus norvegicus
P63074
217
25035
K184
T
H
I
G
R
V
Y
K
E
R
L
G
L
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519751
214
24578
K181
T
H
I
G
R
V
Y
K
E
R
L
G
L
T
Q
Chicken
Gallus gallus
XP_420655
217
25026
K184
T
H
I
G
R
V
Y
K
E
R
L
G
L
P
P
Frog
Xenopus laevis
P48597
213
24616
K180
T
H
I
G
R
V
Y
K
E
R
L
G
L
P
A
Zebra Danio
Brachydanio rerio
Q9DFS6
215
24831
K182
V
H
I
G
R
V
Y
K
E
R
L
G
V
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48598
259
29205
L225
A
L
E
I
G
H
K
L
R
D
A
L
R
L
G
Honey Bee
Apis mellifera
XP_624290
213
24784
R180
M
E
I
G
R
K
L
R
E
R
L
K
I
A
S
Nematode Worm
Caenorhab. elegans
O61955
248
27791
A214
K
P
R
I
C
L
P
A
K
D
P
A
P
V
K
Sea Urchin
Strong. purpuratus
NP_001091928
225
25645
F191
I
T
N
I
G
R
K
F
K
E
R
L
G
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O81481
218
24452
K185
A
A
Q
V
S
I
G
K
Q
W
K
E
L
L
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O23252
235
26501
G201
E
A
A
Q
V
S
I
G
K
Q
W
K
E
F
L
Baker's Yeast
Sacchar. cerevisiae
P07260
213
24236
G180
E
P
L
L
R
I
G
G
K
F
K
Q
V
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.8
90.5
74.7
N.A.
67.6
60.7
N.A.
61.5
61.9
61.5
61.5
N.A.
39
47.1
41.9
46.6
Protein Similarity:
100
77.6
93.2
78
N.A.
79
71.9
N.A.
73.1
73.9
72.7
73.9
N.A.
57.9
63.2
58.4
68.6
P-Site Identity:
100
0
93.3
0
N.A.
60
0
N.A.
0
0
0
6.6
N.A.
26.6
6.6
6.6
53.3
P-Site Similarity:
100
13.3
100
20
N.A.
93.3
6.6
N.A.
6.6
6.6
13.3
13.3
N.A.
46.6
33.3
26.6
80
Percent
Protein Identity:
N.A.
33
N.A.
35.1
31.4
N.A.
Protein Similarity:
N.A.
48.7
N.A.
53.3
53.7
N.A.
P-Site Identity:
N.A.
13.3
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
6
0
0
0
0
6
0
0
6
6
0
6
6
% A
% Cys:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
6
% D
% Glu:
12
6
6
0
0
0
0
0
48
24
0
6
6
0
0
% E
% Phe:
0
0
0
0
0
0
0
6
0
6
0
0
0
6
0
% F
% Gly:
0
0
0
48
30
0
12
12
0
0
0
42
24
0
6
% G
% His:
0
42
12
0
0
6
0
0
0
0
0
0
0
0
0
% H
% Ile:
6
0
48
30
0
12
12
0
0
0
0
0
6
6
0
% I
% Lys:
6
0
0
0
0
6
12
48
42
0
12
12
0
0
12
% K
% Leu:
12
18
6
6
0
6
6
6
0
0
48
30
42
36
6
% L
% Met:
6
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
12
0
0
0
0
6
0
0
0
6
0
6
24
30
% P
% Gln:
0
0
12
6
0
6
0
0
6
6
0
6
0
0
6
% Q
% Arg:
0
0
6
0
53
18
0
6
6
48
24
0
6
0
0
% R
% Ser:
0
0
0
0
6
6
0
0
0
0
0
0
0
12
24
% S
% Thr:
24
6
0
0
0
0
0
0
0
0
0
0
0
6
6
% T
% Val:
24
0
0
12
6
42
12
0
0
0
0
0
12
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
6
6
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
42
18
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _