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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC38A8 All Species: 7.88
Human Site: S342 Identified Species: 14.44
UniProt: A6NNN8 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.42
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NNN8 NP_001073911.1 435 46731 S342 P S A L A D P S G L W V R M P
Chimpanzee Pan troglodytes XP_511008 462 49931 R368 E D V G R E R R R R V L Q T L
Rhesus Macaque Macaca mulatta XP_001110526 624 66685 S506 P R A L A D P S G L W V R M P
Dog Lupus familis XP_546805 445 47499 R371 F W R R S C C R A R G P R T L
Cat Felis silvestris
Mouse Mus musculus Q5HZH7 432 46879 S339 P P V L A D P S G P W V R L P
Rat Rattus norvegicus Q6JWR2 463 49828 R369 E D V G R E R R R R V L Q T L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506288 436 47477 L348 E A L S R M L L T V L W I V T
Chicken Gallus gallus Q5F468 501 55512 F403 L L W A G K E F S W W R H C S
Frog Xenopus laevis Q6DFE7 452 48963 R358 E E P S K E R R R R V L Q T V
Zebra Danio Brachydanio rerio Q6DEL1 465 50660 R367 T D V A K E R R R R I L Q T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001123019 372 41750 D300 D I L Q E Y T D K S I C L F Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786610 461 50468 R362 E W V L R E K R R R V I E T V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39981 480 53305 G383 D E H T Q L S G K Q H V V I T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 39.6 65.7 76.6 N.A. 81.8 40.5 N.A. 66.7 21.3 41.5 39.5 N.A. N.A. 25 N.A. 32.1
Protein Similarity: 100 57.5 66.6 81.5 N.A. 88 57.6 N.A. 79.3 40.5 61.9 60 N.A. N.A. 43.4 N.A. 55.7
P-Site Identity: 100 0 93.3 6.6 N.A. 73.3 0 N.A. 0 6.6 0 0 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 20 93.3 13.3 N.A. 80 20 N.A. 20 6.6 20 20 N.A. N.A. 0 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 40 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 16 16 24 0 0 0 8 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 8 8 0 0 0 0 8 0 8 0 % C
% Asp: 16 24 0 0 0 24 0 8 0 0 0 0 0 0 0 % D
% Glu: 39 16 0 0 8 39 8 0 0 0 0 0 8 0 0 % E
% Phe: 8 0 0 0 0 0 0 8 0 0 0 0 0 8 0 % F
% Gly: 0 0 0 16 8 0 0 8 24 0 8 0 0 0 0 % G
% His: 0 0 8 0 0 0 0 0 0 0 8 0 8 0 0 % H
% Ile: 0 8 0 0 0 0 0 0 0 0 16 8 8 8 0 % I
% Lys: 0 0 0 0 16 8 8 0 16 0 0 0 0 0 0 % K
% Leu: 8 8 16 31 0 8 8 8 0 16 8 31 8 8 31 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 16 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 24 8 8 0 0 0 24 0 0 8 0 8 0 0 24 % P
% Gln: 0 0 0 8 8 0 0 0 0 8 0 0 31 0 8 % Q
% Arg: 0 8 8 8 31 0 31 47 39 47 0 8 31 0 0 % R
% Ser: 0 8 0 16 8 0 8 24 8 8 0 0 0 0 8 % S
% Thr: 8 0 0 8 0 0 8 0 8 0 0 0 0 47 16 % T
% Val: 0 0 39 0 0 0 0 0 0 8 31 31 8 8 16 % V
% Trp: 0 16 8 0 0 0 0 0 0 8 31 8 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _