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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHRS7C
All Species:
28.48
Human Site:
S227
Identified Species:
56.97
UniProt:
A6NNS2
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NNS2
NP_001099041
312
34878
S227
V
S
P
T
F
I
R
S
Y
H
V
Y
P
E
Q
Chimpanzee
Pan troglodytes
XP_511842
308
34444
S223
V
S
P
T
F
I
R
S
Y
H
V
Y
P
E
Q
Rhesus Macaque
Macaca mulatta
XP_001118243
304
34063
S219
V
S
P
T
F
V
R
S
Y
H
V
Y
P
E
Q
Dog
Lupus familis
XP_536640
311
34533
S226
V
S
P
T
F
I
R
S
Y
H
V
D
P
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHS7
311
34449
S226
V
S
P
T
F
I
R
S
Y
R
A
S
P
E
Q
Rat
Rattus norvegicus
Q5RJY4
325
35324
H241
V
I
S
P
G
Y
I
H
T
N
L
S
V
N
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511308
544
58832
T461
V
S
P
G
Y
I
R
T
N
L
S
L
N
A
V
Chicken
Gallus gallus
XP_415576
311
34358
S226
V
N
P
T
F
I
C
S
Y
H
H
Q
P
A
P
Frog
Xenopus laevis
Q0IH28
323
35135
T226
V
N
P
G
Y
I
K
T
N
L
S
L
N
A
V
Zebra Danio
Brachydanio rerio
A8E5C5
324
35163
A226
I
S
H
T
F
I
N
A
G
A
E
N
A
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y140
326
35725
T241
V
S
P
G
Y
I
R
T
Q
L
S
L
N
A
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793326
411
43892
T329
L
S
P
S
Y
I
K
T
N
I
S
L
S
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
84.6
95.1
N.A.
91
39.3
N.A.
25.9
76.9
40.2
54.3
N.A.
32.2
N.A.
N.A.
29.6
Protein Similarity:
100
98.7
86.5
97.4
N.A.
93.5
60
N.A.
38.9
87.8
61.2
71.9
N.A.
53.6
N.A.
N.A.
45.9
P-Site Identity:
100
100
93.3
86.6
N.A.
80
6.6
N.A.
33.3
60
20
26.6
N.A.
33.3
N.A.
N.A.
20
P-Site Similarity:
100
100
100
86.6
N.A.
80
20
N.A.
46.6
66.6
46.6
40
N.A.
46.6
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
9
0
9
9
0
9
42
9
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
9
0
0
34
0
% E
% Phe:
0
0
0
0
59
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
25
9
0
0
0
9
0
0
0
0
9
0
% G
% His:
0
0
9
0
0
0
0
9
0
42
9
0
0
0
0
% H
% Ile:
9
9
0
0
0
84
9
0
0
9
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
0
0
0
0
0
0
0
25
9
34
0
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
17
0
0
0
0
9
0
25
9
0
9
25
9
0
% N
% Pro:
0
0
84
9
0
0
0
0
0
0
0
0
50
0
17
% P
% Gln:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
42
% Q
% Arg:
0
0
0
0
0
0
59
0
0
9
0
0
0
0
0
% R
% Ser:
0
75
9
9
0
0
0
50
0
0
34
17
9
0
0
% S
% Thr:
0
0
0
59
0
0
0
34
9
0
0
0
0
9
0
% T
% Val:
84
0
0
0
0
9
0
0
0
0
34
0
9
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
34
9
0
0
50
0
0
25
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _