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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHRS7C All Species: 21.52
Human Site: S33 Identified Species: 43.03
UniProt: A6NNS2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NNS2 NP_001099041 312 34878 S33 V S R L W S K S A V Q N K V V
Chimpanzee Pan troglodytes XP_511842 308 34444 S30 V S R L W S K S A V Q N K V V
Rhesus Macaque Macaca mulatta XP_001118243 304 34063 S26 N P M G G T G S S R E C H A K
Dog Lupus familis XP_536640 311 34533 S33 V S R L W S K S A V Q N K V V
Cat Felis silvestris
Mouse Mus musculus Q8CHS7 311 34449 S33 A S R L W S K S A V Q N K V V
Rat Rattus norvegicus Q5RJY4 325 35324 A48 L Q R T R S K A Y L R N A V V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511308 544 58832 A269 L Q R I R M K A Y I Q D S V V
Chicken Gallus gallus XP_415576 311 34358 S33 V I W L V S K S A V Q N K V V
Frog Xenopus laevis Q0IH28 323 35135 A32 L Q K L R S G A Y L Q A A V V
Zebra Danio Brachydanio rerio A8E5C5 324 35163 S33 V M R F M S K S V V R N K V V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9Y140 326 35725 N49 F Q A Q K F R N Q L P G K V V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793326 411 43892 A136 L R S Q R R R A G L K D K V V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 84.6 95.1 N.A. 91 39.3 N.A. 25.9 76.9 40.2 54.3 N.A. 32.2 N.A. N.A. 29.6
Protein Similarity: 100 98.7 86.5 97.4 N.A. 93.5 60 N.A. 38.9 87.8 61.2 71.9 N.A. 53.6 N.A. N.A. 45.9
P-Site Identity: 100 100 6.6 100 N.A. 93.3 40 N.A. 33.3 80 33.3 66.6 N.A. 20 N.A. N.A. 20
P-Site Similarity: 100 100 26.6 100 N.A. 93.3 66.6 N.A. 66.6 80 60 73.3 N.A. 40 N.A. N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 0 0 0 0 34 42 0 0 9 17 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 17 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % E
% Phe: 9 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 9 9 0 17 0 9 0 0 9 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 0 9 0 9 0 0 0 0 0 9 0 0 0 0 0 % I
% Lys: 0 0 9 0 9 0 67 0 0 0 9 0 67 0 9 % K
% Leu: 34 0 0 50 0 0 0 0 0 34 0 0 0 0 0 % L
% Met: 0 9 9 0 9 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 0 0 0 0 0 9 0 0 0 59 0 0 0 % N
% Pro: 0 9 0 0 0 0 0 0 0 0 9 0 0 0 0 % P
% Gln: 0 34 0 17 0 0 0 0 9 0 59 0 0 0 0 % Q
% Arg: 0 9 59 0 34 9 17 0 0 9 17 0 0 0 0 % R
% Ser: 0 34 9 0 0 67 0 59 9 0 0 0 9 0 0 % S
% Thr: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % T
% Val: 42 0 0 0 9 0 0 0 9 50 0 0 0 92 92 % V
% Trp: 0 0 9 0 34 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 25 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _