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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHRS7C All Species: 1.21
Human Site: S83 Identified Species: 2.42
UniProt: A6NNS2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NNS2 NP_001099041 312 34878 S83 N L Y D A L I S V A D P S K Q
Chimpanzee Pan troglodytes XP_511842 308 34444 I79 E N L Y D A L I S V A D P S K
Rhesus Macaque Macaca mulatta XP_001118243 304 34063 I75 E N L Y D A L I S V A D P G K
Dog Lupus familis XP_536640 311 34533 I82 Q I L Y D A L I S V A D P S K
Cat Felis silvestris
Mouse Mus musculus Q8CHS7 311 34449 T82 E S L Y A T L T S V A D P S K
Rat Rattus norvegicus Q5RJY4 325 35324 D98 E F T R E L A D S S S S Q G Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511308 544 58832 L317 L E E L V R E L T T N Q P K K
Chicken Gallus gallus XP_415576 311 34358 I82 E A L Y D A L I S V A D P S T
Frog Xenopus laevis Q0IH28 323 35135 N82 D L V Q E L N N M R L K S T Q
Zebra Danio Brachydanio rerio A8E5C5 324 35163 C82 E S L Y D S L C S G S D P S Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9Y140 326 35725 L97 L E R V K K D L L A L D V D P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793326 411 43892 M185 E R V K K E L M G P E I G I P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 84.6 95.1 N.A. 91 39.3 N.A. 25.9 76.9 40.2 54.3 N.A. 32.2 N.A. N.A. 29.6
Protein Similarity: 100 98.7 86.5 97.4 N.A. 93.5 60 N.A. 38.9 87.8 61.2 71.9 N.A. 53.6 N.A. N.A. 45.9
P-Site Identity: 100 0 0 0 N.A. 6.6 13.3 N.A. 6.6 0 26.6 6.6 N.A. 6.6 N.A. N.A. 0
P-Site Similarity: 100 13.3 13.3 20 N.A. 26.6 20 N.A. 20 6.6 46.6 13.3 N.A. 13.3 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 17 34 9 0 0 17 42 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 9 42 0 9 9 0 0 9 59 0 9 0 % D
% Glu: 59 17 9 0 17 9 9 0 0 0 9 0 0 0 0 % E
% Phe: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 9 9 0 0 9 17 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 9 0 0 0 0 9 34 0 0 0 9 0 9 0 % I
% Lys: 0 0 0 9 17 9 0 0 0 0 0 9 0 17 42 % K
% Leu: 17 17 50 9 0 25 59 17 9 0 17 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 9 9 0 0 0 0 0 0 % M
% Asn: 9 17 0 0 0 0 9 9 0 0 9 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 9 0 9 59 0 17 % P
% Gln: 9 0 0 9 0 0 0 0 0 0 0 9 9 0 34 % Q
% Arg: 0 9 9 9 0 9 0 0 0 9 0 0 0 0 0 % R
% Ser: 0 17 0 0 0 9 0 9 59 9 17 9 17 42 0 % S
% Thr: 0 0 9 0 0 9 0 9 9 9 0 0 0 9 9 % T
% Val: 0 0 17 9 9 0 0 0 9 42 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 50 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _