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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHRS7C All Species: 1.82
Human Site: S88 Identified Species: 3.64
UniProt: A6NNS2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NNS2 NP_001099041 312 34878 S88 L I S V A D P S K Q T F T P K
Chimpanzee Pan troglodytes XP_511842 308 34444 P84 A L I S V A D P S K T F T P K
Rhesus Macaque Macaca mulatta XP_001118243 304 34063 P80 A L I S V A D P G K T F T P K
Dog Lupus familis XP_536640 311 34533 P87 A L I S V A D P S K T F T P K
Cat Felis silvestris
Mouse Mus musculus Q8CHS7 311 34449 P87 T L T S V A D P S K T F T P K
Rat Rattus norvegicus Q5RJY4 325 35324 Q103 L A D S S S S Q G Q T H Q P C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511308 544 58832 P322 R E L T T N Q P K K T H K P H
Chicken Gallus gallus XP_415576 311 34358 P87 A L I S V A D P S T T Y T P K
Frog Xenopus laevis Q0IH28 323 35135 S87 L N N M R L K S T Q L H K P H
Zebra Danio Brachydanio rerio A8E5C5 324 35163 P87 S L C S G S D P S Q T F T P K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9Y140 326 35725 V102 K D L L A L D V D P A Y P P T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793326 411 43892 G190 E L M G P E I G I P A H T P H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 84.6 95.1 N.A. 91 39.3 N.A. 25.9 76.9 40.2 54.3 N.A. 32.2 N.A. N.A. 29.6
Protein Similarity: 100 98.7 86.5 97.4 N.A. 93.5 60 N.A. 38.9 87.8 61.2 71.9 N.A. 53.6 N.A. N.A. 45.9
P-Site Identity: 100 33.3 33.3 33.3 N.A. 33.3 26.6 N.A. 20 26.6 26.6 40 N.A. 13.3 N.A. N.A. 13.3
P-Site Similarity: 100 46.6 46.6 46.6 N.A. 53.3 33.3 N.A. 33.3 40 40 46.6 N.A. 26.6 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 34 9 0 0 17 42 0 0 0 0 17 0 0 0 0 % A
% Cys: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 9 % C
% Asp: 0 9 9 0 0 9 59 0 9 0 0 0 0 0 0 % D
% Glu: 9 9 0 0 0 9 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 50 0 0 0 % F
% Gly: 0 0 0 9 9 0 0 9 17 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 34 0 0 25 % H
% Ile: 0 9 34 0 0 0 9 0 9 0 0 0 0 0 0 % I
% Lys: 9 0 0 0 0 0 9 0 17 42 0 0 17 0 59 % K
% Leu: 25 59 17 9 0 17 0 0 0 0 9 0 0 0 0 % L
% Met: 0 0 9 9 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 9 0 0 9 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 9 0 9 59 0 17 0 0 9 100 0 % P
% Gln: 0 0 0 0 0 0 9 9 0 34 0 0 9 0 0 % Q
% Arg: 9 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 9 0 9 59 9 17 9 17 42 0 0 0 0 0 0 % S
% Thr: 9 0 9 9 9 0 0 0 9 9 75 0 67 0 9 % T
% Val: 0 0 0 9 42 0 0 9 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 17 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _