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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHRS7C
All Species:
18.48
Human Site:
T250
Identified Species:
36.97
UniProt:
A6NNS2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NNS2
NP_001099041
312
34878
T250
K
F
F
F
R
K
L
T
Y
G
V
H
P
V
E
Chimpanzee
Pan troglodytes
XP_511842
308
34444
T246
K
F
F
F
R
K
L
T
Y
G
V
H
P
V
E
Rhesus Macaque
Macaca mulatta
XP_001118243
304
34063
T242
K
F
F
F
R
K
L
T
Y
G
V
H
P
V
E
Dog
Lupus familis
XP_536640
311
34533
T249
K
F
F
F
R
K
L
T
Y
G
V
H
P
V
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHS7
311
34449
A249
K
F
F
C
R
K
L
A
Y
G
V
H
P
V
E
Rat
Rattus norvegicus
Q5RJY4
325
35324
A264
G
A
L
D
K
N
T
A
Q
G
R
S
A
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511308
544
58832
E484
V
M
D
K
T
T
S
E
G
R
N
A
A
E
V
Chicken
Gallus gallus
XP_415576
311
34358
T249
K
F
F
F
R
K
V
T
Y
G
V
H
P
A
E
Frog
Xenopus laevis
Q0IH28
323
35135
D249
V
M
D
K
N
T
A
D
G
R
T
P
E
E
V
Zebra Danio
Brachydanio rerio
A8E5C5
324
35163
T249
T
P
T
K
A
T
P
T
N
P
I
W
A
Y
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y140
326
35725
K264
K
V
D
E
T
T
A
K
G
M
S
P
D
K
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793326
411
43892
G352
K
M
D
S
T
T
A
G
G
M
S
T
V
Y
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
84.6
95.1
N.A.
91
39.3
N.A.
25.9
76.9
40.2
54.3
N.A.
32.2
N.A.
N.A.
29.6
Protein Similarity:
100
98.7
86.5
97.4
N.A.
93.5
60
N.A.
38.9
87.8
61.2
71.9
N.A.
53.6
N.A.
N.A.
45.9
P-Site Identity:
100
100
100
93.3
N.A.
86.6
20
N.A.
0
86.6
0
6.6
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
86.6
26.6
N.A.
0
93.3
0
13.3
N.A.
6.6
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
0
25
17
0
0
0
9
25
9
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
34
9
0
0
0
9
0
0
0
0
9
0
9
% D
% Glu:
0
0
0
9
0
0
0
9
0
0
0
0
9
17
50
% E
% Phe:
0
50
50
42
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
0
0
9
34
59
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% I
% Lys:
67
0
0
25
9
50
0
9
0
0
0
0
0
9
0
% K
% Leu:
0
0
9
0
0
0
42
0
0
0
0
0
0
0
9
% L
% Met:
0
25
0
0
0
0
0
0
0
17
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
9
0
0
9
0
9
0
0
0
0
% N
% Pro:
0
9
0
0
0
0
9
0
0
9
0
17
50
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
50
0
0
0
0
17
9
0
0
0
0
% R
% Ser:
0
0
0
9
0
0
9
0
0
0
17
9
0
0
0
% S
% Thr:
9
0
9
0
25
42
9
50
0
0
9
9
0
0
0
% T
% Val:
17
9
0
0
0
0
9
0
0
0
50
0
9
50
34
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
50
0
0
0
0
17
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _