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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENO4
All Species:
5.76
Human Site:
S168
Identified Species:
12.67
UniProt:
A6NNW6
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NNW6
XP_944914
628
68821
S168
L
L
R
I
F
F
A
S
K
V
Q
E
D
K
G
Chimpanzee
Pan troglodytes
XP_001145271
552
60831
E126
L
A
E
A
E
E
A
E
R
A
S
A
V
S
T
Rhesus Macaque
Macaca mulatta
XP_001095040
630
68852
S168
L
L
R
I
F
F
A
S
K
V
Q
E
D
K
E
Dog
Lupus familis
XP_535025
487
52789
V61
F
P
K
N
V
C
S
V
V
I
S
T
H
F
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8C042
619
67864
H168
W
L
R
T
F
F
E
H
K
V
Q
E
D
K
E
Rat
Rattus norvegicus
NP_001127977
602
66248
F165
D
R
R
L
R
I
F
F
E
H
K
V
Q
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512090
642
70002
Y186
V
D
K
L
L
G
K
Y
F
K
E
R
A
R
E
Chicken
Gallus gallus
XP_421780
320
35609
Frog
Xenopus laevis
A9UMP7
572
62400
N146
L
L
K
G
M
S
P
N
E
Q
H
N
I
D
Q
Zebra Danio
Brachydanio rerio
Q08BC6
576
62749
L150
R
E
N
F
S
P
V
L
R
G
F
N
P
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788156
580
64420
E154
V
D
P
T
D
Q
K
E
A
D
D
V
V
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.5
93.1
60.3
N.A.
72.4
71.6
N.A.
58.7
25.6
48.5
37.9
N.A.
N.A.
N.A.
N.A.
33.4
Protein Similarity:
100
82.3
95.2
67
N.A.
82.8
81.6
N.A.
73.6
38.6
63.6
54.9
N.A.
N.A.
N.A.
N.A.
50.9
P-Site Identity:
100
13.3
93.3
0
N.A.
66.6
6.6
N.A.
0
0
13.3
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
20
93.3
20
N.A.
66.6
26.6
N.A.
33.3
0
33.3
6.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
0
28
0
10
10
0
10
10
10
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
19
0
0
10
0
0
0
0
10
10
0
28
10
19
% D
% Glu:
0
10
10
0
10
10
10
19
19
0
10
28
0
0
37
% E
% Phe:
10
0
0
10
28
28
10
10
10
0
10
0
0
10
0
% F
% Gly:
0
0
0
10
0
10
0
0
0
10
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
10
0
10
10
0
10
0
0
% H
% Ile:
0
0
0
19
0
10
0
0
0
10
0
0
10
0
0
% I
% Lys:
0
0
28
0
0
0
19
0
28
10
10
0
0
28
0
% K
% Leu:
37
37
0
19
10
0
0
10
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
10
0
0
0
10
0
0
0
19
0
0
0
% N
% Pro:
0
10
10
0
0
10
10
0
0
0
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
10
28
0
10
0
10
% Q
% Arg:
10
10
37
0
10
0
0
0
19
0
0
10
0
10
0
% R
% Ser:
0
0
0
0
10
10
10
19
0
0
19
0
0
10
0
% S
% Thr:
0
0
0
19
0
0
0
0
0
0
0
10
0
10
19
% T
% Val:
19
0
0
0
10
0
10
10
10
28
0
19
19
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _