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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENO4
All Species:
5.76
Human Site:
S335
Identified Species:
12.67
UniProt:
A6NNW6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NNW6
XP_944914
628
68821
S335
I
I
E
M
M
P
P
S
P
P
K
A
E
T
K
Chimpanzee
Pan troglodytes
XP_001145271
552
60831
T280
T
L
V
I
Q
Q
I
T
G
K
M
S
H
L
G
Rhesus Macaque
Macaca mulatta
XP_001095040
630
68852
S337
A
W
R
C
T
L
P
S
P
P
K
A
E
T
K
Dog
Lupus familis
XP_535025
487
52789
T215
K
R
G
Q
Q
P
I
T
G
K
M
S
H
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8C042
619
67864
P335
N
R
A
M
E
T
L
P
P
P
K
Q
E
T
K
Rat
Rattus norvegicus
NP_001127977
602
66248
P330
N
R
A
M
E
T
L
P
P
P
K
P
E
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512090
642
70002
P352
K
L
L
D
P
V
P
P
H
K
T
E
N
K
K
Chicken
Gallus gallus
XP_421780
320
35609
Y48
L
Y
G
E
L
A
N
Y
F
S
K
F
S
R
A
Frog
Xenopus laevis
A9UMP7
572
62400
Q300
P
P
T
G
L
T
V
Q
Q
S
L
D
M
A
L
Zebra Danio
Brachydanio rerio
Q08BC6
576
62749
I304
L
N
L
L
E
E
I
I
L
M
P
S
S
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788156
580
64420
K308
L
P
L
E
E
G
M
K
Q
V
T
R
V
Y
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.5
93.1
60.3
N.A.
72.4
71.6
N.A.
58.7
25.6
48.5
37.9
N.A.
N.A.
N.A.
N.A.
33.4
Protein Similarity:
100
82.3
95.2
67
N.A.
82.8
81.6
N.A.
73.6
38.6
63.6
54.9
N.A.
N.A.
N.A.
N.A.
50.9
P-Site Identity:
100
0
60
6.6
N.A.
46.6
46.6
N.A.
13.3
6.6
0
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
26.6
60
20
N.A.
46.6
46.6
N.A.
20
20
6.6
26.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
19
0
0
10
0
0
0
0
0
19
0
10
10
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
10
19
37
10
0
0
0
0
0
10
37
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% F
% Gly:
0
0
19
10
0
10
0
0
19
0
0
0
0
0
19
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
19
0
10
% H
% Ile:
10
10
0
10
0
0
28
10
0
0
0
0
0
0
0
% I
% Lys:
19
0
0
0
0
0
0
10
0
28
46
0
0
10
46
% K
% Leu:
28
19
28
10
19
10
19
0
10
0
10
0
0
19
19
% L
% Met:
0
0
0
28
10
0
10
0
0
10
19
0
10
0
0
% M
% Asn:
19
10
0
0
0
0
10
0
0
0
0
0
10
0
0
% N
% Pro:
10
19
0
0
10
19
28
28
37
37
10
10
0
0
0
% P
% Gln:
0
0
0
10
19
10
0
10
19
0
0
10
0
0
0
% Q
% Arg:
0
28
10
0
0
0
0
0
0
0
0
10
0
10
0
% R
% Ser:
0
0
0
0
0
0
0
19
0
19
0
28
19
10
0
% S
% Thr:
10
0
10
0
10
28
0
19
0
0
19
0
0
37
0
% T
% Val:
0
0
10
0
0
10
10
0
0
10
0
0
10
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
10
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _