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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENO4
All Species:
5.76
Human Site:
S452
Identified Species:
12.67
UniProt:
A6NNW6
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NNW6
XP_944914
628
68821
S452
D
P
F
R
K
E
D
S
E
Q
W
D
S
I
Y
Chimpanzee
Pan troglodytes
XP_001145271
552
60831
C390
Y
H
A
L
G
S
R
C
Y
I
I
A
G
T
A
Rhesus Macaque
Macaca mulatta
XP_001095040
630
68852
S454
D
P
F
R
K
E
D
S
E
Q
W
D
S
I
Y
Dog
Lupus familis
XP_535025
487
52789
C325
Y
N
T
L
G
S
R
C
Y
I
I
A
G
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8C042
619
67864
A452
D
P
F
R
K
E
D
A
E
Q
W
D
S
L
Y
Rat
Rattus norvegicus
NP_001127977
602
66248
D440
P
S
I
I
A
L
I
D
P
F
R
K
E
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512090
642
70002
N469
D
P
L
R
K
E
D
N
E
Q
W
K
N
I
C
Chicken
Gallus gallus
XP_421780
320
35609
K158
L
G
E
Y
F
S
K
K
V
E
E
K
K
E
V
Frog
Xenopus laevis
A9UMP7
572
62400
A410
D
L
I
N
R
Q
P
A
I
L
A
L
L
D
P
Zebra Danio
Brachydanio rerio
Q08BC6
576
62749
Y414
P
D
E
L
V
D
I
Y
E
G
L
I
N
K
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788156
580
64420
D418
P
A
I
I
A
L
I
D
P
L
R
K
Q
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.5
93.1
60.3
N.A.
72.4
71.6
N.A.
58.7
25.6
48.5
37.9
N.A.
N.A.
N.A.
N.A.
33.4
Protein Similarity:
100
82.3
95.2
67
N.A.
82.8
81.6
N.A.
73.6
38.6
63.6
54.9
N.A.
N.A.
N.A.
N.A.
50.9
P-Site Identity:
100
0
100
0
N.A.
86.6
0
N.A.
66.6
0
6.6
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
0
100
0
N.A.
100
0
N.A.
80
6.6
26.6
26.6
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
19
0
0
19
0
0
10
19
0
10
19
% A
% Cys:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
10
% C
% Asp:
46
10
0
0
0
10
37
19
0
0
0
28
0
28
0
% D
% Glu:
0
0
19
0
0
37
0
0
46
10
10
0
10
10
0
% E
% Phe:
0
0
28
0
10
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
10
0
0
19
0
0
0
0
10
0
0
19
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
28
19
0
0
28
0
10
19
19
10
0
28
0
% I
% Lys:
0
0
0
0
37
0
10
10
0
0
0
37
10
10
0
% K
% Leu:
10
10
10
28
0
19
0
0
0
19
10
10
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
10
0
0
0
10
0
0
0
0
19
0
0
% N
% Pro:
28
37
0
0
0
0
10
0
19
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
10
0
0
0
37
0
0
10
0
0
% Q
% Arg:
0
0
0
37
10
0
19
0
0
0
19
0
0
0
0
% R
% Ser:
0
10
0
0
0
28
0
19
0
0
0
0
28
0
19
% S
% Thr:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% T
% Val:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
37
0
0
0
0
% W
% Tyr:
19
0
0
10
0
0
0
10
19
0
0
0
0
0
37
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _