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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENO4
All Species:
15.15
Human Site:
S531
Identified Species:
33.33
UniProt:
A6NNW6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NNW6
XP_944914
628
68821
S531
G
S
T
E
G
E
S
S
D
D
S
L
V
D
L
Chimpanzee
Pan troglodytes
XP_001145271
552
60831
R469
L
A
V
G
L
G
V
R
F
I
K
L
G
G
L
Rhesus Macaque
Macaca mulatta
XP_001095040
630
68852
S533
G
S
T
E
G
E
S
S
D
D
S
L
V
D
L
Dog
Lupus familis
XP_535025
487
52789
R404
L
A
I
G
L
G
V
R
F
I
K
L
G
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8C042
619
67864
S531
G
S
T
D
S
E
S
S
D
D
S
L
V
D
L
Rat
Rattus norvegicus
NP_001127977
602
66248
G519
K
K
H
L
A
V
F
G
S
T
D
S
E
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512090
642
70002
S548
G
S
S
D
G
E
S
S
D
D
S
L
A
D
L
Chicken
Gallus gallus
XP_421780
320
35609
N237
A
K
A
G
A
S
I
N
H
V
P
L
Y
L
H
Frog
Xenopus laevis
A9UMP7
572
62400
N489
F
K
L
I
E
G
E
N
R
V
T
I
L
G
C
Zebra Danio
Brachydanio rerio
Q08BC6
576
62749
S493
T
I
S
D
L
I
Q
S
I
A
E
H
K
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788156
580
64420
S497
A
S
I
T
T
I
S
S
V
P
G
D
T
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.5
93.1
60.3
N.A.
72.4
71.6
N.A.
58.7
25.6
48.5
37.9
N.A.
N.A.
N.A.
N.A.
33.4
Protein Similarity:
100
82.3
95.2
67
N.A.
82.8
81.6
N.A.
73.6
38.6
63.6
54.9
N.A.
N.A.
N.A.
N.A.
50.9
P-Site Identity:
100
13.3
100
13.3
N.A.
86.6
0
N.A.
80
6.6
0
6.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
20
100
20
N.A.
93.3
0
N.A.
93.3
13.3
26.6
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
19
10
0
19
0
0
0
0
10
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
28
0
0
0
0
37
37
10
10
0
37
10
% D
% Glu:
0
0
0
19
10
37
10
0
0
0
10
0
10
10
0
% E
% Phe:
10
0
0
0
0
0
10
0
19
0
0
0
0
0
0
% F
% Gly:
37
0
0
28
28
28
0
10
0
0
10
0
19
28
0
% G
% His:
0
0
10
0
0
0
0
0
10
0
0
10
0
0
10
% H
% Ile:
0
10
19
10
0
19
10
0
10
19
0
10
0
0
0
% I
% Lys:
10
28
0
0
0
0
0
0
0
0
19
0
10
0
0
% K
% Leu:
19
0
10
10
28
0
0
0
0
0
0
64
10
10
55
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
19
10
0
0
0
0
0
0
% R
% Ser:
0
46
19
0
10
10
46
55
10
0
37
10
0
19
10
% S
% Thr:
10
0
28
10
10
0
0
0
0
10
10
0
10
0
10
% T
% Val:
0
0
10
0
0
10
19
0
10
19
0
0
28
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _