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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ENO4 All Species: 14.24
Human Site: S534 Identified Species: 31.33
UniProt: A6NNW6 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NNW6 XP_944914 628 68821 S534 E G E S S D D S L V D L A V G
Chimpanzee Pan troglodytes XP_001145271 552 60831 K472 G L G V R F I K L G G L S R G
Rhesus Macaque Macaca mulatta XP_001095040 630 68852 S536 E G E S S D D S L V D L A V G
Dog Lupus familis XP_535025 487 52789 K407 G L G V R F I K L G G L S R G
Cat Felis silvestris
Mouse Mus musculus Q8C042 619 67864 S534 D S E S S D D S L V D L A V G
Rat Rattus norvegicus NP_001127977 602 66248 D522 L A V F G S T D S E S S D D S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512090 642 70002 S551 D G E S S D D S L A D L A V G
Chicken Gallus gallus XP_421780 320 35609 P240 G A S I N H V P L Y L H I A L
Frog Xenopus laevis A9UMP7 572 62400 T492 I E G E N R V T I L G C P C E
Zebra Danio Brachydanio rerio Q08BC6 576 62749 E496 D L I Q S I A E H K E T I L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788156 580 64420 G500 T T I S S V P G D T S D T F L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 81.5 93.1 60.3 N.A. 72.4 71.6 N.A. 58.7 25.6 48.5 37.9 N.A. N.A. N.A. N.A. 33.4
Protein Similarity: 100 82.3 95.2 67 N.A. 82.8 81.6 N.A. 73.6 38.6 63.6 54.9 N.A. N.A. N.A. N.A. 50.9
P-Site Identity: 100 20 100 20 N.A. 86.6 0 N.A. 86.6 6.6 0 6.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 26.6 100 26.6 N.A. 93.3 0 N.A. 93.3 13.3 26.6 26.6 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 0 0 0 0 10 0 0 10 0 0 37 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 0 % C
% Asp: 28 0 0 0 0 37 37 10 10 0 37 10 10 10 0 % D
% Glu: 19 10 37 10 0 0 0 10 0 10 10 0 0 0 10 % E
% Phe: 0 0 0 10 0 19 0 0 0 0 0 0 0 10 0 % F
% Gly: 28 28 28 0 10 0 0 10 0 19 28 0 0 0 55 % G
% His: 0 0 0 0 0 10 0 0 10 0 0 10 0 0 0 % H
% Ile: 10 0 19 10 0 10 19 0 10 0 0 0 19 0 0 % I
% Lys: 0 0 0 0 0 0 0 19 0 10 0 0 0 0 0 % K
% Leu: 10 28 0 0 0 0 0 0 64 10 10 55 0 10 19 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 19 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 10 10 0 0 0 0 10 0 0 % P
% Gln: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 19 10 0 0 0 0 0 0 0 19 0 % R
% Ser: 0 10 10 46 55 10 0 37 10 0 19 10 19 0 10 % S
% Thr: 10 10 0 0 0 0 10 10 0 10 0 10 10 0 0 % T
% Val: 0 0 10 19 0 10 19 0 0 28 0 0 0 37 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _