KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENO4
All Species:
8.48
Human Site:
T274
Identified Species:
18.67
UniProt:
A6NNW6
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NNW6
XP_944914
628
68821
T274
H
N
Q
E
Q
P
T
T
L
S
M
P
L
L
M
Chimpanzee
Pan troglodytes
XP_001145271
552
60831
P231
E
V
I
C
I
P
H
P
E
L
T
T
K
Q
E
Rhesus Macaque
Macaca mulatta
XP_001095040
630
68852
M273
K
H
N
Q
E
Q
P
M
L
F
M
P
L
L
M
Dog
Lupus familis
XP_535025
487
52789
L166
L
G
N
N
P
L
Y
L
N
I
A
L
L
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8C042
619
67864
T276
H
D
Q
E
Q
P
S
T
F
S
M
P
L
L
M
Rat
Rattus norvegicus
NP_001127977
602
66248
T271
H
D
Q
E
Q
P
S
T
F
S
M
P
L
L
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512090
642
70002
E292
H
N
Q
E
L
P
K
E
L
V
M
P
L
L
M
Chicken
Gallus gallus
XP_421780
320
35609
Frog
Xenopus laevis
A9UMP7
572
62400
I251
K
T
P
L
Y
L
H
I
A
T
L
R
N
E
K
Zebra Danio
Brachydanio rerio
Q08BC6
576
62749
E255
A
V
A
K
T
A
A
E
L
L
G
T
P
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788156
580
64420
A259
Y
E
H
I
C
N
A
A
G
N
V
E
V
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.5
93.1
60.3
N.A.
72.4
71.6
N.A.
58.7
25.6
48.5
37.9
N.A.
N.A.
N.A.
N.A.
33.4
Protein Similarity:
100
82.3
95.2
67
N.A.
82.8
81.6
N.A.
73.6
38.6
63.6
54.9
N.A.
N.A.
N.A.
N.A.
50.9
P-Site Identity:
100
6.6
40
6.6
N.A.
80
80
N.A.
73.3
0
0
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
6.6
60
6.6
N.A.
93.3
93.3
N.A.
73.3
0
13.3
20
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
10
19
10
10
0
10
0
0
0
0
% A
% Cys:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
19
0
0
0
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
10
10
0
37
10
0
0
19
10
0
0
10
0
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
19
10
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
10
0
10
0
0
0
0
% G
% His:
37
10
10
0
0
0
19
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
10
10
0
0
10
0
10
0
0
0
0
0
% I
% Lys:
19
0
0
10
0
0
10
0
0
0
0
0
10
10
10
% K
% Leu:
10
0
0
10
10
19
0
10
37
19
10
10
55
55
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
46
0
0
0
46
% M
% Asn:
0
19
19
10
0
10
0
0
10
10
0
0
10
0
0
% N
% Pro:
0
0
10
0
10
46
10
10
0
0
0
46
10
0
0
% P
% Gln:
0
0
37
10
28
10
0
0
0
0
0
0
0
10
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
0
0
0
0
0
0
19
0
0
28
0
0
0
0
0
% S
% Thr:
0
10
0
0
10
0
10
28
0
10
10
19
0
0
0
% T
% Val:
0
19
0
0
0
0
0
0
0
10
10
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
10
0
10
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _