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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP27X
All Species:
32.12
Human Site:
S117
Identified Species:
50.48
UniProt:
A6NNY8
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NNY8
NP_001138545.1
438
49630
S117
R
H
R
C
E
M
P
S
P
E
L
C
L
V
C
Chimpanzee
Pan troglodytes
XP_521085
711
79749
S402
K
H
K
C
I
M
T
S
P
S
L
C
L
V
C
Rhesus Macaque
Macaca mulatta
XP_001100790
710
79332
S401
K
H
K
C
I
M
T
S
P
S
L
C
L
V
C
Dog
Lupus familis
XP_548999
579
65084
S258
R
H
R
C
E
M
P
S
P
E
L
C
L
V
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8CEG8
438
49580
S117
R
H
R
C
E
M
P
S
P
E
L
C
L
V
C
Rat
Rattus norvegicus
B2GUX4
565
62681
G251
D
F
R
Q
E
V
P
G
G
G
R
A
Q
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511206
488
55972
S178
R
H
K
C
E
M
Q
S
P
S
S
C
L
V
C
Chicken
Gallus gallus
O57429
357
40913
L73
L
M
S
E
F
A
K
L
I
Q
L
L
W
T
S
Frog
Xenopus laevis
Q6GNI6
523
60030
S213
R
H
K
C
E
M
Q
S
P
N
S
C
L
V
C
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
S198
R
H
K
C
E
M
Q
S
N
S
C
L
V
C
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR1
735
82440
S436
R
H
D
C
G
S
K
S
S
H
K
C
L
V
C
Honey Bee
Apis mellifera
XP_395389
502
57164
T198
R
H
H
C
P
Q
P
T
R
C
L
V
C
E
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786312
585
65894
R198
K
H
H
C
E
N
E
R
S
R
D
N
C
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LEW0
557
63499
P216
Q
H
N
R
D
L
C
P
R
R
T
M
G
L
L
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
T123
K
Y
W
D
D
V
C
T
K
T
M
V
P
S
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.5
45.2
74.6
N.A.
96.3
20.1
N.A.
73.5
23.7
65.7
65.8
N.A.
26.5
53.3
N.A.
46.8
Protein Similarity:
100
51.9
51.2
75.1
N.A.
97.7
34.3
N.A.
79
39.5
71.6
72.9
N.A.
38.2
65.7
N.A.
59.4
P-Site Identity:
100
66.6
66.6
100
N.A.
100
20
N.A.
73.3
6.6
73.3
40
N.A.
53.3
33.3
N.A.
20
P-Site Similarity:
100
80
80
100
N.A.
100
26.6
N.A.
80
13.3
80
53.3
N.A.
53.3
40
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.7
23.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.8
40.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
0
0
0
0
7
0
0
0
% A
% Cys:
0
0
0
74
0
0
14
0
0
7
7
54
14
7
54
% C
% Asp:
7
0
7
7
14
0
0
0
0
0
7
0
0
0
0
% D
% Glu:
0
0
0
7
54
0
7
0
0
20
0
0
0
14
7
% E
% Phe:
0
7
0
0
7
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
7
0
0
7
7
7
0
0
7
0
0
% G
% His:
0
80
14
0
0
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
0
0
14
0
0
0
7
0
0
0
0
0
0
% I
% Lys:
27
0
34
0
0
0
14
0
7
0
7
0
0
0
0
% K
% Leu:
7
0
0
0
0
7
0
7
0
0
47
14
54
14
14
% L
% Met:
0
7
0
0
0
54
0
0
0
0
7
7
0
0
7
% M
% Asn:
0
0
7
0
0
7
0
0
7
7
0
7
0
0
0
% N
% Pro:
0
0
0
0
7
0
34
7
47
0
0
0
7
0
0
% P
% Gln:
7
0
0
7
0
7
20
0
0
7
0
0
7
0
0
% Q
% Arg:
54
0
27
7
0
0
0
7
14
14
7
0
0
0
0
% R
% Ser:
0
0
7
0
0
7
0
60
14
27
14
0
0
7
7
% S
% Thr:
0
0
0
0
0
0
14
14
0
7
7
0
0
7
0
% T
% Val:
0
0
0
0
0
14
0
0
0
0
0
14
7
54
14
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _