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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP27X
All Species:
30.61
Human Site:
S139
Identified Species:
48.1
UniProt:
A6NNY8
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NNY8
NP_001138545.1
438
49630
S139
E
L
Y
S
G
N
P
S
P
H
V
P
Y
K
L
Chimpanzee
Pan troglodytes
XP_521085
711
79749
T424
A
M
Y
S
G
S
R
T
P
H
I
P
Y
K
L
Rhesus Macaque
Macaca mulatta
XP_001100790
710
79332
T423
A
M
Y
S
G
S
R
T
P
H
I
P
Y
K
L
Dog
Lupus familis
XP_548999
579
65084
S280
E
L
Y
S
G
N
P
S
P
H
V
P
Y
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8CEG8
438
49580
S139
E
L
Y
S
G
N
P
S
P
H
V
P
Y
K
L
Rat
Rattus norvegicus
B2GUX4
565
62681
D273
I
G
A
L
W
H
P
D
S
C
E
A
V
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511206
488
55972
S200
E
F
Y
S
G
H
R
S
P
H
I
P
Y
R
L
Chicken
Gallus gallus
O57429
357
40913
I95
P
S
E
F
K
T
Q
I
Q
R
Y
A
P
R
F
Frog
Xenopus laevis
Q6GNI6
523
60030
S235
E
F
Y
S
G
H
R
S
P
H
I
P
Y
R
L
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
P220
F
Y
S
G
H
R
S
P
H
I
P
F
R
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR1
735
82440
S458
E
F
Y
S
G
S
R
S
P
L
S
L
H
R
L
Honey Bee
Apis mellifera
XP_395389
502
57164
L220
Y
S
G
S
K
A
P
L
T
L
H
K
L
L
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786312
585
65894
R220
Q
E
F
Y
S
G
I
R
S
V
H
I
P
Y
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LEW0
557
63499
S238
V
I
F
S
A
M
F
S
G
D
R
T
P
Y
S
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
T145
G
L
I
N
M
G
S
T
C
F
M
S
S
I
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.5
45.2
74.6
N.A.
96.3
20.1
N.A.
73.5
23.7
65.7
65.8
N.A.
26.5
53.3
N.A.
46.8
Protein Similarity:
100
51.9
51.2
75.1
N.A.
97.7
34.3
N.A.
79
39.5
71.6
72.9
N.A.
38.2
65.7
N.A.
59.4
P-Site Identity:
100
60
60
100
N.A.
100
6.6
N.A.
66.6
0
66.6
6.6
N.A.
46.6
13.3
N.A.
0
P-Site Similarity:
100
86.6
86.6
100
N.A.
100
13.3
N.A.
86.6
6.6
86.6
6.6
N.A.
66.6
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.7
23.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.8
40.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
7
0
7
7
0
0
0
0
0
14
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
7
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
0
% D
% Glu:
40
7
7
0
0
0
0
0
0
0
7
0
0
0
0
% E
% Phe:
7
20
14
7
0
0
7
0
0
7
0
7
0
0
7
% F
% Gly:
7
7
7
7
54
14
0
0
7
0
0
0
0
0
0
% G
% His:
0
0
0
0
7
20
0
0
7
47
14
0
7
0
7
% H
% Ile:
7
7
7
0
0
0
7
7
0
7
27
7
0
7
0
% I
% Lys:
0
0
0
0
14
0
0
0
0
0
0
7
0
34
0
% K
% Leu:
0
27
0
7
0
0
0
7
0
14
0
7
7
14
67
% L
% Met:
0
14
0
0
7
7
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
0
0
7
0
20
0
0
0
0
0
0
0
7
0
% N
% Pro:
7
0
0
0
0
0
34
7
54
0
7
47
20
0
7
% P
% Gln:
7
0
0
0
0
0
7
0
7
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
7
34
7
0
7
7
0
7
27
7
% R
% Ser:
0
14
7
67
7
20
14
47
14
0
7
7
7
0
7
% S
% Thr:
0
0
0
0
0
7
0
20
7
0
0
7
0
0
0
% T
% Val:
7
0
0
0
0
0
0
0
0
7
20
0
7
0
0
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
7
54
7
0
0
0
0
0
0
7
0
47
14
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _