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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP27X
All Species:
11.52
Human Site:
S249
Identified Species:
18.1
UniProt:
A6NNY8
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NNY8
NP_001138545.1
438
49630
S249
P
M
S
P
G
R
E
S
S
V
N
G
E
S
H
Chimpanzee
Pan troglodytes
XP_521085
711
79749
S505
C
Q
A
C
H
S
V
S
T
T
I
D
P
C
W
Rhesus Macaque
Macaca mulatta
XP_001100790
710
79332
P509
S
V
S
T
T
I
D
P
C
W
D
I
S
L
D
Dog
Lupus familis
XP_548999
579
65084
S390
P
M
S
P
G
R
E
S
S
V
N
G
E
S
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8CEG8
438
49580
S249
P
M
S
P
G
R
E
S
S
L
N
G
E
S
H
Rat
Rattus norvegicus
B2GUX4
565
62681
C381
F
V
G
Q
L
K
S
C
L
K
C
Q
A
C
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511206
488
55972
P286
G
V
S
T
T
I
D
P
F
W
D
I
S
L
D
Chicken
Gallus gallus
O57429
357
40913
L175
V
G
Q
L
K
S
S
L
T
C
S
E
C
G
Y
Frog
Xenopus laevis
Q6GNI6
523
60030
P321
G
V
S
T
T
I
D
P
F
W
D
I
S
L
D
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
I302
C
H
G
V
S
T
T
I
D
P
F
W
D
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR1
735
82440
M544
I
D
Q
I
F
T
G
M
L
Q
S
D
V
V
C
Honey Bee
Apis mellifera
XP_395389
502
57164
A315
S
L
D
L
G
P
A
A
S
A
S
G
S
D
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786312
585
65894
S330
A
P
L
T
S
S
S
S
L
H
N
G
D
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LEW0
557
63499
R349
P
A
D
C
R
K
N
R
Y
S
G
G
P
S
V
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
D237
L
A
G
Y
S
Q
Q
D
A
H
E
F
W
Q
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.5
45.2
74.6
N.A.
96.3
20.1
N.A.
73.5
23.7
65.7
65.8
N.A.
26.5
53.3
N.A.
46.8
Protein Similarity:
100
51.9
51.2
75.1
N.A.
97.7
34.3
N.A.
79
39.5
71.6
72.9
N.A.
38.2
65.7
N.A.
59.4
P-Site Identity:
100
6.6
6.6
100
N.A.
93.3
0
N.A.
6.6
0
6.6
0
N.A.
0
20
N.A.
26.6
P-Site Similarity:
100
20
26.6
100
N.A.
100
13.3
N.A.
26.6
20
26.6
6.6
N.A.
6.6
40
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.7
23.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.8
40.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
14
7
0
0
0
7
7
7
7
0
0
7
0
0
% A
% Cys:
14
0
0
14
0
0
0
7
7
7
7
0
7
14
7
% C
% Asp:
0
7
14
0
0
0
20
7
7
0
20
14
14
7
20
% D
% Glu:
0
0
0
0
0
0
20
0
0
0
7
7
20
0
0
% E
% Phe:
7
0
0
0
7
0
0
0
14
0
7
7
0
0
7
% F
% Gly:
14
7
20
0
27
0
7
0
0
0
7
40
0
7
14
% G
% His:
0
7
0
0
7
0
0
0
0
14
0
0
0
0
20
% H
% Ile:
7
0
0
7
0
20
0
7
0
0
7
20
0
7
0
% I
% Lys:
0
0
0
0
7
14
0
0
0
7
0
0
0
0
0
% K
% Leu:
7
7
7
14
7
0
0
7
20
7
0
0
0
20
0
% L
% Met:
0
20
0
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
0
0
0
27
0
0
0
0
% N
% Pro:
27
7
0
20
0
7
0
20
0
7
0
0
14
0
0
% P
% Gln:
0
7
14
7
0
7
7
0
0
7
0
7
0
7
0
% Q
% Arg:
0
0
0
0
7
20
0
7
0
0
0
0
0
0
0
% R
% Ser:
14
0
40
0
20
20
20
34
27
7
20
0
27
34
14
% S
% Thr:
0
0
0
27
20
14
7
0
14
7
0
0
0
0
0
% T
% Val:
7
27
0
7
0
0
7
0
0
14
0
0
7
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
20
0
7
7
0
7
% W
% Tyr:
0
0
0
7
0
0
0
0
7
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _