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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP27X
All Species:
13.64
Human Site:
S278
Identified Species:
21.43
UniProt:
A6NNY8
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NNY8
NP_001138545.1
438
49630
S278
T
R
P
E
H
L
G
S
S
A
K
I
K
C
G
Chimpanzee
Pan troglodytes
XP_521085
711
79749
D534
S
Q
N
P
E
R
A
D
S
A
V
S
R
D
D
Rhesus Macaque
Macaca mulatta
XP_001100790
710
79332
R538
R
A
D
G
T
V
S
R
D
D
H
I
P
G
I
Dog
Lupus familis
XP_548999
579
65084
S419
T
R
P
E
H
L
G
S
S
A
K
I
K
C
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8CEG8
438
49580
S278
T
R
P
E
H
L
G
S
S
A
K
I
K
C
G
Rat
Rattus norvegicus
B2GUX4
565
62681
A410
P
I
P
K
K
G
F
A
G
G
K
V
S
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511206
488
55972
G315
S
D
G
S
V
V
N
G
E
S
H
V
S
G
T
Chicken
Gallus gallus
O57429
357
40913
E204
I
P
K
K
G
Y
G
E
V
T
L
M
D
C
L
Frog
Xenopus laevis
Q6GNI6
523
60030
G350
S
D
A
G
V
V
N
G
E
S
H
V
S
G
T
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
V331
P
G
S
D
G
S
V
V
N
G
D
S
H
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR1
735
82440
E573
D
I
S
L
D
L
G
E
T
T
T
H
G
G
V
Honey Bee
Apis mellifera
XP_395389
502
57164
S344
T
R
A
E
H
L
G
S
S
A
K
I
K
C
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786312
585
65894
T359
D
D
C
L
R
R
F
T
R
P
E
Y
L
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LEW0
557
63499
P378
T
R
S
E
K
L
G
P
D
Q
K
L
N
C
Q
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
A266
N
A
K
E
V
S
R
A
N
N
K
Q
C
E
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.5
45.2
74.6
N.A.
96.3
20.1
N.A.
73.5
23.7
65.7
65.8
N.A.
26.5
53.3
N.A.
46.8
Protein Similarity:
100
51.9
51.2
75.1
N.A.
97.7
34.3
N.A.
79
39.5
71.6
72.9
N.A.
38.2
65.7
N.A.
59.4
P-Site Identity:
100
13.3
6.6
100
N.A.
100
13.3
N.A.
0
13.3
0
0
N.A.
13.3
86.6
N.A.
0
P-Site Similarity:
100
33.3
13.3
100
N.A.
100
33.3
N.A.
26.6
26.6
26.6
13.3
N.A.
20
86.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.7
23.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.8
40.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
14
0
0
0
7
14
0
34
0
0
0
0
0
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
0
7
40
7
% C
% Asp:
14
20
7
7
7
0
0
7
14
7
7
0
7
7
7
% D
% Glu:
0
0
0
40
7
0
0
14
14
0
7
0
0
7
0
% E
% Phe:
0
0
0
0
0
0
14
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
7
14
14
7
47
14
7
14
0
0
7
34
20
% G
% His:
0
0
0
0
27
0
0
0
0
0
20
7
7
0
0
% H
% Ile:
7
14
0
0
0
0
0
0
0
0
0
34
0
0
7
% I
% Lys:
0
0
14
14
14
0
0
0
0
0
47
0
27
0
0
% K
% Leu:
0
0
0
14
0
40
0
0
0
0
7
7
7
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
7
0
7
0
0
0
14
0
14
7
0
0
7
0
0
% N
% Pro:
14
7
27
7
0
0
0
7
0
7
0
0
7
7
0
% P
% Gln:
0
7
0
0
0
0
0
0
0
7
0
7
0
0
7
% Q
% Arg:
7
34
0
0
7
14
7
7
7
0
0
0
7
0
7
% R
% Ser:
20
0
20
7
0
14
7
27
34
14
0
14
20
0
20
% S
% Thr:
34
0
0
0
7
0
0
7
7
14
7
0
0
0
14
% T
% Val:
0
0
0
0
20
20
7
7
7
0
7
20
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _