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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP27X All Species: 22.12
Human Site: S34 Identified Species: 34.76
UniProt: A6NNY8 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NNY8 NP_001138545.1 438 49630 S34 A S T S T E V S H Q Q C S V P
Chimpanzee Pan troglodytes XP_521085 711 79749 S320 T S T S T D V S H Q Q F M T S
Rhesus Macaque Macaca mulatta XP_001100790 710 79332 S319 T S T S T D V S H Q Q F M T S
Dog Lupus familis XP_548999 579 65084 S175 A S T S T E V S H Q Q C S V M
Cat Felis silvestris
Mouse Mus musculus Q8CEG8 438 49580 S34 A S T S T E V S Q Q Q C S V P
Rat Rattus norvegicus B2GUX4 565 62681 T155 P P T L R R S T S L R R L G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511206 488 55972 S95 A F T P T V V S H Y Q C T M T
Chicken Gallus gallus O57429 357 40913
Frog Xenopus laevis Q6GNI6 523 60030 S130 V F S P A L V S P Y Q Y T M T
Zebra Danio Brachydanio rerio A6H8I0 506 58102 Q115 E Q I A K E E Q R K A W K L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVR1 735 82440 S241 D A S S A V M S E T G C R H Y
Honey Bee Apis mellifera XP_395389 502 57164 W115 L G V A K A Q W S E S A K S L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786312 585 65894 R115 E Q I S Q E E R L N C S K F H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LEW0 557 63499 F126 V V V S K Q L F G L G M S V K
Baker's Yeast Sacchar. cerevisiae P50102 471 53605 E38 L N H S V P K E K F L N T M K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 45.5 45.2 74.6 N.A. 96.3 20.1 N.A. 73.5 23.7 65.7 65.8 N.A. 26.5 53.3 N.A. 46.8
Protein Similarity: 100 51.9 51.2 75.1 N.A. 97.7 34.3 N.A. 79 39.5 71.6 72.9 N.A. 38.2 65.7 N.A. 59.4
P-Site Identity: 100 60 60 93.3 N.A. 93.3 6.6 N.A. 53.3 0 20 6.6 N.A. 20 0 N.A. 13.3
P-Site Similarity: 100 66.6 66.6 93.3 N.A. 93.3 20 N.A. 66.6 0 40 26.6 N.A. 40 13.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 33.7 23.5 N.A.
Protein Similarity: N.A. N.A. N.A. 50.8 40.5 N.A.
P-Site Identity: N.A. N.A. N.A. 20 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 27 7 0 14 14 7 0 0 0 0 7 7 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 7 34 0 0 0 % C
% Asp: 7 0 0 0 0 14 0 0 0 0 0 0 0 0 0 % D
% Glu: 14 0 0 0 0 34 14 7 7 7 0 0 0 0 0 % E
% Phe: 0 14 0 0 0 0 0 7 0 7 0 14 0 7 0 % F
% Gly: 0 7 0 0 0 0 0 0 7 0 14 0 0 7 7 % G
% His: 0 0 7 0 0 0 0 0 34 0 0 0 0 7 7 % H
% Ile: 0 0 14 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 20 0 7 0 7 7 0 0 20 0 14 % K
% Leu: 14 0 0 7 0 7 7 0 7 14 7 0 7 7 7 % L
% Met: 0 0 0 0 0 0 7 0 0 0 0 7 14 20 7 % M
% Asn: 0 7 0 0 0 0 0 0 0 7 0 7 0 0 0 % N
% Pro: 7 7 0 14 0 7 0 0 7 0 0 0 0 0 14 % P
% Gln: 0 14 0 0 7 7 7 7 7 34 47 0 0 0 7 % Q
% Arg: 0 0 0 0 7 7 0 7 7 0 7 7 7 0 0 % R
% Ser: 0 34 14 60 0 0 7 54 14 0 7 7 27 7 14 % S
% Thr: 14 0 47 0 40 0 0 7 0 7 0 0 20 14 14 % T
% Val: 14 7 14 0 7 14 47 0 0 0 0 0 0 27 0 % V
% Trp: 0 0 0 0 0 0 0 7 0 0 0 7 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 14 0 7 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _