Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP27X All Species: 11.52
Human Site: S342 Identified Species: 18.1
UniProt: A6NNY8 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.5
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NNY8 NP_001138545.1 438 49630 S342 M T P F M A S S K E S R M N G
Chimpanzee Pan troglodytes XP_521085 711 79749 K597 I V A C F H L K R F E H V G K
Rhesus Macaque Macaca mulatta XP_001100790 710 79332 T610 K Q R R K I N T F I S F P L E
Dog Lupus familis XP_548999 579 65084 S483 M T P F M A S S K E S R M N G
Cat Felis silvestris
Mouse Mus musculus Q8CEG8 438 49580 S342 M T P F M A S S K E T R V N G
Rat Rattus norvegicus B2GUX4 565 62681 I473 F S T S R G S I K K S S V G V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511206 488 55972 K384 H S A K L R R K I T T Y V S F
Chicken Gallus gallus O57429 357 40913 S265 S E A R I R A S K L T T F V N
Frog Xenopus laevis Q6GNI6 523 60030 K419 H S A K L R R K I T T Y V S F
Zebra Danio Brachydanio rerio A6H8I0 506 58102 R392 V A C F H L K R F E H S A K L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVR1 735 82440 R634 V V S F H L K R F E H S A L I
Honey Bee Apis mellifera XP_395389 502 57164 R408 M T P F M S H R R N G N N N S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786312 585 65894 H430 M T P Y M S T H R R A N G L S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LEW0 557 63499 R453 I G K R F G N R I F A F D G E
Baker's Yeast Sacchar. cerevisiae P50102 471 53605 L358 I H K L P S V L V L Q L K R F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 45.5 45.2 74.6 N.A. 96.3 20.1 N.A. 73.5 23.7 65.7 65.8 N.A. 26.5 53.3 N.A. 46.8
Protein Similarity: 100 51.9 51.2 75.1 N.A. 97.7 34.3 N.A. 79 39.5 71.6 72.9 N.A. 38.2 65.7 N.A. 59.4
P-Site Identity: 100 0 6.6 100 N.A. 86.6 20 N.A. 0 13.3 0 13.3 N.A. 13.3 40 N.A. 26.6
P-Site Similarity: 100 20 20 100 N.A. 100 40 N.A. 33.3 33.3 33.3 20 N.A. 20 53.3 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. 33.7 23.5 N.A.
Protein Similarity: N.A. N.A. N.A. 50.8 40.5 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 27 0 0 20 7 0 0 0 14 0 14 0 0 % A
% Cys: 0 0 7 7 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % D
% Glu: 0 7 0 0 0 0 0 0 0 34 7 0 0 0 14 % E
% Phe: 7 0 0 40 14 0 0 0 20 14 0 14 7 0 20 % F
% Gly: 0 7 0 0 0 14 0 0 0 0 7 0 7 20 20 % G
% His: 14 7 0 0 14 7 7 7 0 0 14 7 0 0 0 % H
% Ile: 20 0 0 0 7 7 0 7 20 7 0 0 0 0 7 % I
% Lys: 7 0 14 14 7 0 14 20 34 7 0 0 7 7 7 % K
% Leu: 0 0 0 7 14 14 7 7 0 14 0 7 0 20 7 % L
% Met: 34 0 0 0 34 0 0 0 0 0 0 0 14 0 0 % M
% Asn: 0 0 0 0 0 0 14 0 0 7 0 14 7 27 7 % N
% Pro: 0 0 34 0 7 0 0 0 0 0 0 0 7 0 0 % P
% Gln: 0 7 0 0 0 0 0 0 0 0 7 0 0 0 0 % Q
% Arg: 0 0 7 20 7 20 14 27 20 7 0 20 0 7 0 % R
% Ser: 7 20 7 7 0 20 27 27 0 0 27 20 0 14 14 % S
% Thr: 0 34 7 0 0 0 7 7 0 14 27 7 0 0 0 % T
% Val: 14 14 0 0 0 0 7 0 7 0 0 0 34 7 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 0 0 0 0 0 0 14 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _