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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP27X All Species: 12.73
Human Site: S383 Identified Species: 20
UniProt: A6NNY8 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NNY8 NP_001138545.1 438 49630 S383 L E S G H Y T S F I R H H K D
Chimpanzee Pan troglodytes XP_521085 711 79749 P638 S R M K E G Q P P T D C V P N
Rhesus Macaque Macaca mulatta XP_001100790 710 79332 F651 N E N K Y S L F A V I N H H G
Dog Lupus familis XP_548999 579 65084 S524 L E S G H Y T S F I R H H K D
Cat Felis silvestris
Mouse Mus musculus Q8CEG8 438 49580 S383 L E S G H Y T S F I R H H R D
Rat Rattus norvegicus B2GUX4 565 62681 V514 L C N H S G S V H Y G H Y T A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511206 488 55972 K425 D S L N N D N K Y S L F A V V
Chicken Gallus gallus O57429 357 40913 M306 S N H S G T T M G G H Y T A Y
Frog Xenopus laevis Q6GNI6 523 60030 K460 D S L H N D N K Y S L F A V V
Zebra Danio Brachydanio rerio A6H8I0 506 58102 Q433 R M N G Q Y Q Q P V D S L N N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVR1 735 82440 L675 Y G D F R F S L Y A V V N H V
Honey Bee Apis mellifera XP_395389 502 57164 T449 N H E G S L E T G H Y T A F I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786312 585 65894 C471 L E A G H Y T C Y V R Q H Q D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LEW0 557 63499 T494 L E S G H Y V T Y L R L K G L
Baker's Yeast Sacchar. cerevisiae P50102 471 53605 K399 C S T K E K D K H S E N G K V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 45.5 45.2 74.6 N.A. 96.3 20.1 N.A. 73.5 23.7 65.7 65.8 N.A. 26.5 53.3 N.A. 46.8
Protein Similarity: 100 51.9 51.2 75.1 N.A. 97.7 34.3 N.A. 79 39.5 71.6 72.9 N.A. 38.2 65.7 N.A. 59.4
P-Site Identity: 100 0 13.3 100 N.A. 93.3 13.3 N.A. 0 6.6 0 13.3 N.A. 0 6.6 N.A. 60
P-Site Similarity: 100 6.6 40 100 N.A. 100 33.3 N.A. 13.3 13.3 13.3 33.3 N.A. 26.6 13.3 N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. 33.7 23.5 N.A.
Protein Similarity: N.A. N.A. N.A. 50.8 40.5 N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 66.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 0 0 0 0 7 7 0 0 20 7 7 % A
% Cys: 7 7 0 0 0 0 0 7 0 0 0 7 0 0 0 % C
% Asp: 14 0 7 0 0 14 7 0 0 0 14 0 0 0 27 % D
% Glu: 0 40 7 0 14 0 7 0 0 0 7 0 0 0 0 % E
% Phe: 0 0 0 7 0 7 0 7 20 0 0 14 0 7 0 % F
% Gly: 0 7 0 47 7 14 0 0 14 7 7 0 7 7 7 % G
% His: 0 7 7 14 34 0 0 0 14 7 7 27 34 14 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 20 7 0 0 0 7 % I
% Lys: 0 0 0 20 0 7 0 20 0 0 0 0 7 20 0 % K
% Leu: 40 0 14 0 0 7 7 7 0 7 14 7 7 0 7 % L
% Met: 0 7 7 0 0 0 0 7 0 0 0 0 0 0 0 % M
% Asn: 14 7 20 7 14 0 14 0 0 0 0 14 7 7 14 % N
% Pro: 0 0 0 0 0 0 0 7 14 0 0 0 0 7 0 % P
% Gln: 0 0 0 0 7 0 14 7 0 0 0 7 0 7 0 % Q
% Arg: 7 7 0 0 7 0 0 0 0 0 34 0 0 7 0 % R
% Ser: 14 20 27 7 14 7 14 20 0 20 0 7 0 0 0 % S
% Thr: 0 0 7 0 0 7 34 14 0 7 0 7 7 7 0 % T
% Val: 0 0 0 0 0 0 7 7 0 20 7 7 7 14 27 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 7 40 0 0 34 7 7 7 7 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _