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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP27X
All Species:
17.27
Human Site:
S39
Identified Species:
27.14
UniProt:
A6NNY8
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NNY8
NP_001138545.1
438
49630
S39
E
V
S
H
Q
Q
C
S
V
P
G
L
G
E
K
Chimpanzee
Pan troglodytes
XP_521085
711
79749
M325
D
V
S
H
Q
Q
F
M
T
S
G
F
E
D
K
Rhesus Macaque
Macaca mulatta
XP_001100790
710
79332
M324
D
V
S
H
Q
Q
F
M
T
S
G
T
E
D
K
Dog
Lupus familis
XP_548999
579
65084
S180
E
V
S
H
Q
Q
C
S
V
M
G
L
G
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8CEG8
438
49580
S39
E
V
S
Q
Q
Q
C
S
V
P
G
L
G
E
K
Rat
Rattus norvegicus
B2GUX4
565
62681
L160
R
S
T
S
L
R
R
L
G
G
F
P
G
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511206
488
55972
T100
V
V
S
H
Y
Q
C
T
M
T
G
I
G
E
K
Chicken
Gallus gallus
O57429
357
40913
Frog
Xenopus laevis
Q6GNI6
523
60030
T135
L
V
S
P
Y
Q
Y
T
M
T
G
V
G
E
K
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
K120
E
E
Q
R
K
A
W
K
L
Q
G
I
G
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR1
735
82440
R246
V
M
S
E
T
G
C
R
H
Y
Q
S
Y
V
K
Honey Bee
Apis mellifera
XP_395389
502
57164
K120
A
Q
W
S
E
S
A
K
S
L
S
F
G
E
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786312
585
65894
K120
E
E
R
L
N
C
S
K
F
H
G
I
V
Q
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LEW0
557
63499
S131
Q
L
F
G
L
G
M
S
V
K
S
G
A
D
V
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
T43
P
K
E
K
F
L
N
T
M
K
C
G
T
C
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.5
45.2
74.6
N.A.
96.3
20.1
N.A.
73.5
23.7
65.7
65.8
N.A.
26.5
53.3
N.A.
46.8
Protein Similarity:
100
51.9
51.2
75.1
N.A.
97.7
34.3
N.A.
79
39.5
71.6
72.9
N.A.
38.2
65.7
N.A.
59.4
P-Site Identity:
100
46.6
46.6
93.3
N.A.
93.3
6.6
N.A.
60
0
46.6
33.3
N.A.
20
13.3
N.A.
13.3
P-Site Similarity:
100
60
60
93.3
N.A.
93.3
20
N.A.
80
0
66.6
53.3
N.A.
26.6
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.7
23.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.8
40.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
7
7
0
0
0
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
7
34
0
0
0
7
0
0
7
0
% C
% Asp:
14
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% D
% Glu:
34
14
7
7
7
0
0
0
0
0
0
0
14
47
0
% E
% Phe:
0
0
7
0
7
0
14
0
7
0
7
14
0
0
7
% F
% Gly:
0
0
0
7
0
14
0
0
7
7
60
14
54
0
7
% G
% His:
0
0
0
34
0
0
0
0
7
7
0
0
0
0
7
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% I
% Lys:
0
7
0
7
7
0
0
20
0
14
0
0
0
0
60
% K
% Leu:
7
7
0
7
14
7
0
7
7
7
0
20
0
0
0
% L
% Met:
0
7
0
0
0
0
7
14
20
7
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
7
0
0
0
0
0
0
0
0
% N
% Pro:
7
0
0
7
0
0
0
0
0
14
0
7
0
7
7
% P
% Gln:
7
7
7
7
34
47
0
0
0
7
7
0
0
7
0
% Q
% Arg:
7
0
7
7
0
7
7
7
0
0
0
0
0
0
0
% R
% Ser:
0
7
54
14
0
7
7
27
7
14
14
7
0
0
0
% S
% Thr:
0
0
7
0
7
0
0
20
14
14
0
7
7
0
0
% T
% Val:
14
47
0
0
0
0
0
0
27
0
0
7
7
7
7
% V
% Trp:
0
0
7
0
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
14
0
7
0
0
7
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _