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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP27X
All Species:
16.97
Human Site:
S72
Identified Species:
26.67
UniProt:
A6NNY8
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NNY8
NP_001138545.1
438
49630
S72
R
R
R
R
I
T
S
S
F
T
I
G
L
R
G
Chimpanzee
Pan troglodytes
XP_521085
711
79749
V357
K
K
R
R
K
K
S
V
Y
T
V
G
L
R
G
Rhesus Macaque
Macaca mulatta
XP_001100790
710
79332
V356
K
K
R
R
K
K
S
V
Y
T
V
G
L
R
G
Dog
Lupus familis
XP_548999
579
65084
S213
R
R
R
R
I
T
S
S
F
T
I
G
L
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8CEG8
438
49580
S72
R
R
R
R
I
A
S
S
F
T
I
G
L
R
G
Rat
Rattus norvegicus
B2GUX4
565
62681
L206
K
M
A
H
H
T
L
L
L
G
S
G
H
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511206
488
55972
N133
K
R
R
K
I
T
T
N
C
T
I
G
L
R
G
Chicken
Gallus gallus
O57429
357
40913
C28
L
R
N
L
G
N
T
C
F
M
N
S
I
L
Q
Frog
Xenopus laevis
Q6GNI6
523
60030
N168
K
R
R
K
I
T
T
N
C
T
I
G
L
R
G
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
N153
K
R
R
K
I
T
A
N
C
T
I
G
L
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR1
735
82440
N391
R
R
R
L
V
R
P
N
Q
T
I
G
L
R
G
Honey Bee
Apis mellifera
XP_395389
502
57164
N153
R
R
R
R
V
V
E
N
S
T
I
G
L
R
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786312
585
65894
S153
T
R
K
K
V
S
G
S
S
T
I
G
L
R
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LEW0
557
63499
T171
R
D
R
R
E
K
W
T
F
P
L
G
L
R
G
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
S78
H
S
H
F
L
S
H
S
K
Q
I
G
H
I
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.5
45.2
74.6
N.A.
96.3
20.1
N.A.
73.5
23.7
65.7
65.8
N.A.
26.5
53.3
N.A.
46.8
Protein Similarity:
100
51.9
51.2
75.1
N.A.
97.7
34.3
N.A.
79
39.5
71.6
72.9
N.A.
38.2
65.7
N.A.
59.4
P-Site Identity:
100
53.3
53.3
100
N.A.
93.3
20
N.A.
66.6
13.3
66.6
66.6
N.A.
60
66.6
N.A.
53.3
P-Site Similarity:
100
80
80
100
N.A.
93.3
26.6
N.A.
93.3
26.6
93.3
93.3
N.A.
73.3
80
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.7
23.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.8
40.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
7
7
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
7
20
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
7
0
7
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
7
0
0
0
0
34
0
0
0
0
0
7
% F
% Gly:
0
0
0
0
7
0
7
0
0
7
0
94
0
0
87
% G
% His:
7
0
7
7
7
0
7
0
0
0
0
0
14
0
0
% H
% Ile:
0
0
0
0
40
0
0
0
0
0
67
0
7
7
0
% I
% Lys:
40
14
7
27
14
20
0
0
7
0
0
0
0
0
0
% K
% Leu:
7
0
0
14
7
0
7
7
7
0
7
0
80
7
0
% L
% Met:
0
7
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
7
0
34
0
0
7
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
7
0
0
7
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
7
7
0
0
0
0
7
% Q
% Arg:
40
67
74
47
0
7
0
0
0
0
0
0
0
80
0
% R
% Ser:
0
7
0
0
0
14
34
34
14
0
7
7
0
0
0
% S
% Thr:
7
0
0
0
0
40
20
7
0
74
0
0
0
0
0
% T
% Val:
0
0
0
0
20
7
0
14
0
0
14
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
14
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _