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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP27X
All Species:
13.33
Human Site:
T238
Identified Species:
20.95
UniProt:
A6NNY8
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NNY8
NP_001138545.1
438
49630
T238
L
D
L
P
G
S
C
T
S
F
W
P
M
S
P
Chimpanzee
Pan troglodytes
XP_521085
711
79749
S494
I
F
T
G
G
L
Q
S
D
V
T
C
Q
A
C
Rhesus Macaque
Macaca mulatta
XP_001100790
710
79332
Q498
L
Q
S
D
V
T
C
Q
A
C
H
S
V
S
T
Dog
Lupus familis
XP_548999
579
65084
T379
L
D
L
P
G
S
C
T
S
F
W
P
M
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8CEG8
438
49580
T238
L
D
L
P
G
S
C
T
S
F
W
P
M
S
P
Rat
Rattus norvegicus
B2GUX4
565
62681
I370
L
E
R
E
D
S
K
I
V
D
L
F
V
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511206
488
55972
Q275
L
Q
S
D
V
T
C
Q
V
C
H
G
V
S
T
Chicken
Gallus gallus
O57429
357
40913
S164
E
R
E
D
S
R
V
S
D
L
F
V
G
Q
L
Frog
Xenopus laevis
Q6GNI6
523
60030
Q310
L
Q
S
D
V
T
C
Q
V
C
H
G
V
S
T
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
T291
G
G
L
Q
S
D
V
T
C
Q
V
C
H
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR1
735
82440
C533
S
S
H
C
Y
G
Q
C
N
C
I
I
D
Q
I
Honey Bee
Apis mellifera
XP_395389
502
57164
F304
V
S
T
T
I
D
P
F
W
D
I
S
L
D
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786312
585
65894
S319
L
D
L
G
P
S
S
S
S
N
S
A
P
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LEW0
557
63499
N338
S
L
T
L
D
S
M
N
G
F
S
P
A
D
C
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
I226
L
L
T
C
A
W
K
I
N
Q
N
L
A
G
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.5
45.2
74.6
N.A.
96.3
20.1
N.A.
73.5
23.7
65.7
65.8
N.A.
26.5
53.3
N.A.
46.8
Protein Similarity:
100
51.9
51.2
75.1
N.A.
97.7
34.3
N.A.
79
39.5
71.6
72.9
N.A.
38.2
65.7
N.A.
59.4
P-Site Identity:
100
6.6
20
100
N.A.
100
13.3
N.A.
20
0
20
13.3
N.A.
0
0
N.A.
33.3
P-Site Similarity:
100
26.6
40
100
N.A.
100
26.6
N.A.
33.3
13.3
33.3
13.3
N.A.
6.6
13.3
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.7
23.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.8
40.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
0
7
0
0
7
14
7
0
% A
% Cys:
0
0
0
14
0
0
40
7
7
27
0
14
0
0
14
% C
% Asp:
0
27
0
27
14
14
0
0
14
14
0
0
7
14
0
% D
% Glu:
7
7
7
7
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
7
0
0
0
0
0
7
0
27
7
7
0
0
0
% F
% Gly:
7
7
0
14
27
7
0
0
7
0
0
14
7
20
0
% G
% His:
0
0
7
0
0
0
0
0
0
0
20
0
7
0
0
% H
% Ile:
7
0
0
0
7
0
0
14
0
0
14
7
0
0
7
% I
% Lys:
0
0
0
0
0
0
14
0
0
0
0
0
0
0
0
% K
% Leu:
60
14
34
7
0
7
0
0
0
7
7
7
7
7
14
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
0
20
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
14
7
7
0
0
0
0
% N
% Pro:
0
0
0
20
7
0
7
0
0
0
0
27
7
0
20
% P
% Gln:
0
20
0
7
0
0
14
20
0
14
0
0
7
14
7
% Q
% Arg:
0
7
7
0
0
7
0
0
0
0
0
0
0
0
0
% R
% Ser:
14
14
20
0
14
40
7
20
27
0
14
14
0
40
0
% S
% Thr:
0
0
27
7
0
20
0
27
0
0
7
0
0
0
27
% T
% Val:
7
0
0
0
20
0
14
0
20
7
7
7
27
0
7
% V
% Trp:
0
0
0
0
0
7
0
0
7
0
20
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _