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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP27X All Species: 23.64
Human Site: T70 Identified Species: 37.14
UniProt: A6NNY8 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NNY8 NP_001138545.1 438 49630 T70 N P R R R R I T S S F T I G L
Chimpanzee Pan troglodytes XP_521085 711 79749 K355 P K K K R R K K S V Y T V G L
Rhesus Macaque Macaca mulatta XP_001100790 710 79332 K354 P K K K R R K K S V Y T V G L
Dog Lupus familis XP_548999 579 65084 T211 N P R R R R I T S S F T I G L
Cat Felis silvestris
Mouse Mus musculus Q8CEG8 438 49580 A70 N P R R R R I A S S F T I G L
Rat Rattus norvegicus B2GUX4 565 62681 T204 D D K M A H H T L L L G S G H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511206 488 55972 T131 N P K R R K I T T N C T I G L
Chicken Gallus gallus O57429 357 40913 N26 T G L R N L G N T C F M N S I
Frog Xenopus laevis Q6GNI6 523 60030 T166 N P K R R K I T T N C T I G L
Zebra Danio Brachydanio rerio A6H8I0 506 58102 T151 N P K R R K I T A N C T I G L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVR1 735 82440 R389 N A R R R L V R P N Q T I G L
Honey Bee Apis mellifera XP_395389 502 57164 V151 H P R R R R V V E N S T I G L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786312 585 65894 S151 N P T R K K V S G S S T I G L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LEW0 557 63499 K169 S P R D R R E K W T F P L G L
Baker's Yeast Sacchar. cerevisiae P50102 471 53605 S76 W N H S H F L S H S K Q I G H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 45.5 45.2 74.6 N.A. 96.3 20.1 N.A. 73.5 23.7 65.7 65.8 N.A. 26.5 53.3 N.A. 46.8
Protein Similarity: 100 51.9 51.2 75.1 N.A. 97.7 34.3 N.A. 79 39.5 71.6 72.9 N.A. 38.2 65.7 N.A. 59.4
P-Site Identity: 100 40 40 100 N.A. 93.3 13.3 N.A. 66.6 13.3 66.6 66.6 N.A. 53.3 60 N.A. 53.3
P-Site Similarity: 100 66.6 66.6 100 N.A. 93.3 26.6 N.A. 93.3 26.6 93.3 93.3 N.A. 66.6 80 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. 33.7 23.5 N.A.
Protein Similarity: N.A. N.A. N.A. 50.8 40.5 N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 66.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 7 0 0 7 7 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 7 20 0 0 0 0 % C
% Asp: 7 7 0 7 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 7 0 7 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 7 0 0 0 0 34 0 0 0 0 % F
% Gly: 0 7 0 0 0 0 7 0 7 0 0 7 0 94 0 % G
% His: 7 0 7 0 7 7 7 0 7 0 0 0 0 0 14 % H
% Ile: 0 0 0 0 0 0 40 0 0 0 0 0 67 0 7 % I
% Lys: 0 14 40 14 7 27 14 20 0 0 7 0 0 0 0 % K
% Leu: 0 0 7 0 0 14 7 0 7 7 7 0 7 0 80 % L
% Met: 0 0 0 7 0 0 0 0 0 0 0 7 0 0 0 % M
% Asn: 54 7 0 0 7 0 0 7 0 34 0 0 7 0 0 % N
% Pro: 14 60 0 0 0 0 0 0 7 0 0 7 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 7 7 0 0 0 % Q
% Arg: 0 0 40 67 74 47 0 7 0 0 0 0 0 0 0 % R
% Ser: 7 0 0 7 0 0 0 14 34 34 14 0 7 7 0 % S
% Thr: 7 0 7 0 0 0 0 40 20 7 0 74 0 0 0 % T
% Val: 0 0 0 0 0 0 20 7 0 14 0 0 14 0 0 % V
% Trp: 7 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 14 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _