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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP27X
All Species:
14.24
Human Site:
Y364
Identified Species:
22.38
UniProt:
A6NNY8
Number Species:
14
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NNY8
NP_001138545.1
438
49630
Y364
S
G
N
N
E
N
K
Y
S
L
F
A
V
V
N
Chimpanzee
Pan troglodytes
XP_521085
711
79749
L619
F
I
S
F
P
L
E
L
D
M
T
P
F
L
A
Rhesus Macaque
Macaca mulatta
XP_001100790
710
79332
M632
A
S
T
K
E
S
R
M
K
E
G
Q
P
P
A
Dog
Lupus familis
XP_548999
579
65084
Y505
S
G
N
D
E
N
K
Y
S
L
F
A
V
V
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8CEG8
438
49580
Y364
S
A
N
N
E
N
K
Y
S
L
F
A
V
V
N
Rat
Rattus norvegicus
B2GUX4
565
62681
D495
S
L
G
D
F
A
S
D
K
V
G
S
P
V
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511206
488
55972
E406
P
F
M
A
S
S
K
E
S
R
M
N
G
Q
Y
Chicken
Gallus gallus
O57429
357
40913
S287
L
R
E
F
A
S
Q
S
C
N
H
A
V
Y
N
Frog
Xenopus laevis
Q6GNI6
523
60030
E441
P
F
M
A
S
S
K
E
S
R
M
N
G
Q
Y
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
D414
V
S
F
P
L
E
L
D
M
T
P
F
M
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR1
735
82440
D656
I
Q
F
P
V
E
F
D
M
T
P
F
M
S
E
Honey Bee
Apis mellifera
XP_395389
502
57164
F430
K
N
G
E
D
M
A
F
S
D
N
R
Y
S
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786312
585
65894
Y452
T
T
T
S
D
N
Q
Y
S
L
F
A
V
V
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LEW0
557
63499
F475
S
S
S
P
S
A
E
F
E
I
F
A
V
V
T
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
I380
N
R
K
L
D
D
F
I
E
F
P
T
Y
L
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.5
45.2
74.6
N.A.
96.3
20.1
N.A.
73.5
23.7
65.7
65.8
N.A.
26.5
53.3
N.A.
46.8
Protein Similarity:
100
51.9
51.2
75.1
N.A.
97.7
34.3
N.A.
79
39.5
71.6
72.9
N.A.
38.2
65.7
N.A.
59.4
P-Site Identity:
100
0
6.6
93.3
N.A.
93.3
13.3
N.A.
13.3
20
13.3
0
N.A.
0
6.6
N.A.
60
P-Site Similarity:
100
26.6
26.6
100
N.A.
93.3
33.3
N.A.
20
33.3
20
13.3
N.A.
6.6
20
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.7
23.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.8
40.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
14
7
14
7
0
0
0
0
40
0
7
14
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
0
0
14
20
7
0
20
7
7
0
0
0
0
0
% D
% Glu:
0
0
7
7
27
14
14
14
14
7
0
0
0
0
7
% E
% Phe:
7
14
14
14
7
0
14
14
0
7
34
14
7
0
0
% F
% Gly:
0
14
14
0
0
0
0
0
0
0
14
0
14
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
7
7
0
0
0
0
0
7
0
7
0
0
0
0
0
% I
% Lys:
7
0
7
7
0
0
34
0
14
0
0
0
0
0
0
% K
% Leu:
7
7
0
7
7
7
7
7
0
27
0
0
0
14
7
% L
% Met:
0
0
14
0
0
7
0
7
14
7
14
0
14
0
0
% M
% Asn:
7
7
20
14
0
27
0
0
0
7
7
14
0
0
40
% N
% Pro:
14
0
0
20
7
0
0
0
0
0
20
7
14
7
0
% P
% Gln:
0
7
0
0
0
0
14
0
0
0
0
7
0
14
0
% Q
% Arg:
0
14
0
0
0
0
7
0
0
14
0
7
0
0
0
% R
% Ser:
34
20
14
7
20
27
7
7
47
0
0
7
0
14
7
% S
% Thr:
7
7
14
0
0
0
0
0
0
14
7
7
0
0
7
% T
% Val:
7
0
0
0
7
0
0
0
0
7
0
0
40
40
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
27
0
0
0
0
14
7
20
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _